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Authors: Claire Dalmay 1 ; Jun-Jung Lai 1 ; Laurent Griscom 1 ; Olivier Français 1 ; Bruno Le Pioufle 1 ; Frédéric Subra 2 ; Patrick Tauc 2 and Joseph Lautru 3

Affiliations: 1 CNRS SATIE, IFR d’Alembert and ENS Cachan, France ; 2 CNRS LBPA, IFR d’Alembert and ENS Cachan, France ; 3 IFR d’Alembert and ENS Cachan, France

ISBN: 978-989-8425-37-9

Keyword(s): Parylene-C patterning, Cell patterning, Cell orientation, Cell migration.

Related Ontology Subjects/Areas/Topics: Biomaterials ; Biomedical Engineering ; Biomedical Instruments and Devices ; Imaging and Visualization Devices ; Technologies Evaluation

Abstract: A new method for the positioning and orientation of adherent cells on a culture substrate is presented. We demonstrate the ability of a micro patterned parylene-C film deposited on a fused silica substrate to position, isolate and/or orientate cells. Such features are crucial for the development of future biodevices for the analysis and treatment of single-cell or organized cell tissues. In particular, our method is advantageous for controlling the orientation of the cells within an organized tissue while being exposed to an electrical field. The developed method does not require any chemical treatment of the cells or any additional surface modification and is suitable for integration into a microfluidic system.

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Paper citation in several formats:
Dalmay, C.; Lai, J.; Griscom, L.; Français, O.; Le Pioufle, B.; Subra, F.; Tauc, P. and Lautru, J. (2011). POSITIONING AND ORIENTATION OF ADHERENT CELLS IN A MICROFLUIDIC CHIP USING THE MICRO PATTERNING OF A PARYLENE-C FILM.In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011) ISBN 978-989-8425-37-9, pages 212-215. DOI: 10.5220/0003156702120215

@conference{biodevices11,
author={Claire Dalmay. and Jun{-}Jung Lai. and Laurent Griscom. and Olivier Fran\c{C}ais. and Bruno Le Pioufle. and Frédéric Subra. and Patrick Tauc. and Joseph Lautru.},
title={POSITIONING AND ORIENTATION OF ADHERENT CELLS IN A MICROFLUIDIC CHIP USING THE MICRO PATTERNING OF A PARYLENE-C FILM},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011)},
year={2011},
pages={212-215},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003156702120215},
isbn={978-989-8425-37-9},
}

TY - CONF

JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011)
TI - POSITIONING AND ORIENTATION OF ADHERENT CELLS IN A MICROFLUIDIC CHIP USING THE MICRO PATTERNING OF A PARYLENE-C FILM
SN - 978-989-8425-37-9
AU - Dalmay, C.
AU - Lai, J.
AU - Griscom, L.
AU - Français, O.
AU - Le Pioufle, B.
AU - Subra, F.
AU - Tauc, P.
AU - Lautru, J.
PY - 2011
SP - 212
EP - 215
DO - 10.5220/0003156702120215

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