Authors:
Manolis Tsiknakis
1
;
Stelios Sfakianakis
1
;
Stefan Rueping
2
;
Oswaldo Trelles
3
;
Thierry Siestang
4
;
Brecht Claerhout
5
and
Vasiilis Virvilis
6
Affiliations:
1
Institute of Computer Science, Foundation for Research and Technology - Hellas, Greece
;
2
Fraunhofer IAIS, Schloss Birlinghoven, Germany
;
3
University of Malaga, Spain
;
4
Swiss Institute of Bioinformatics, Switzerland
;
5
Custodix NV, Belgium
;
6
Biovista S.A., Greece
Keyword(s):
Ontology-based Biomedical Database Integration, Semantic Mediation, Ontologies, Post-genomic Clinical Trials, Service Oriented Architectures.
Related
Ontology
Subjects/Areas/Topics:
Affective Computing
;
Applications
;
Artificial Intelligence
;
Biomedical Engineering
;
Biomedical Signal Processing
;
Business Analytics
;
Cardiovascular Technologies
;
Cloud Computing
;
Cognitive Informatics
;
Collaboration and e-Services
;
Complex Systems Modeling and Simulation
;
Computing and Telecommunications in Cardiology
;
Confidentiality and Data Security
;
Data Engineering
;
Data Mining
;
Databases and Datawarehousing
;
Databases and Information Systems Integration
;
Datamining
;
Development of Assistive Technology
;
Devices
;
Distributed and Mobile Software Systems
;
e-Business
;
e-Commerce in the Health Sector
;
e-Health
;
Enterprise Information Systems
;
Expert Systems
;
Health Engineering and Technology Applications
;
Health Information Systems
;
Hospital Management Systems
;
Human-Computer Interaction
;
Human-Machine Interfaces for Disabled Persons
;
ICT for Cognitive Disabilities
;
ICT, Ageing and Disability
;
Integration/Interoperability
;
Interoperability
;
Knowledge Engineering and Ontology Development
;
Knowledge Management and Information Sharing
;
Knowledge-Based Systems
;
Medical and Nursing Informatics
;
Mobile Technologies
;
Mobile Technologies for Healthcare Applications
;
Neural Rehabilitation
;
Neurotechnology, Electronics and Informatics
;
Online Medical Applications
;
Ontologies and the Semantic Web
;
Physiological Computing Systems
;
Physiological Modeling
;
Platforms and Applications
;
Practice Based Research Methods for Assistive Technology
;
Semantic Interoperability
;
Sensor Networks
;
Signal Processing
;
Simulation and Modeling
;
Socio-Economic Issues of Assistive Technology
;
Soft Computing
;
Software Agents and Internet Computing
;
Software and Architectures
;
Software Engineering
;
Symbolic Systems
;
Telemedicine
;
Therapeutic Systems and Technologies
;
Wearable Sensors and Systems
Abstract:
This paper presents the architectural considerations of the Advancing Clinico-Genomic Trials on Cancer (ACGT) project aiming at delivering a European Biomedical Grid in support of efficient knowledge discovery in the context of post-genomic clinical trials on cancer. Our main research challenge in ACGT is the requirement to develop an infrastructure able to produce, use, and deploy knowledge as a basic element of advanced applications, which will mainly constitute a Biomedical Knowledge Grid. Our approach to offer semantic modelling of available services and data sources to support high level services and dynamic services for discovery and composition will be presented. In particular, ontologies and metadata are the basic elements through which Grid intelligence services can be developed, and the current achievements of the project in this domain will be discussed.