Authors:
A. Lopes
1
;
A. Gabriel
1
;
J. Machado
1
;
P. Ribeiro
1
;
R. Gomes
2
;
João M. P. Coelho
2
;
C. O. Silva
3
;
C. P. Reis
4
;
J. P. Santos
1
and
P. Vieira
1
Affiliations:
1
Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, Portugal
;
2
Faculdade de Ciências da Universidade de Lisboa, Portugal
;
3
Lusófona University, Portugal
;
4
Faculdade de Ciências da Universidade de Lisboa and Lusófona University, Portugal
Keyword(s):
Near Infrared, Spectroscopy, GAMOS, Monte Carlo, Phototerapy, Breast Cancer.
Related
Ontology
Subjects/Areas/Topics:
Biomedical Engineering
;
Biomedical Equipment
;
Biomedical Instrumentation
;
Biomedical Instruments and Devices
;
Emerging Technologies
;
Telecommunications
;
Wireless and Mobile Technologies
;
Wireless Information Networks and Systems
Abstract:
Radiation therapy is one of many common treatments applied to breast cancer. Most usual radiation sources applied are ionizing radiation, such as g-rays and X-rays, and non-ionizing radiation such as ultraviolet radiation.
The possibility of using near infrared light to photoactivate a drug inside an 8 cm diameter biological object is discussed in this work via Monte Carlo simulations. Two simulation setups performed in the Geant4/GAMOS framework are presented in order to study the viability of photoactivating a drug by using several near infrared light sources. The overall objective of this technique is to minimize energy concentrated at objects surface and maximize it in a predefined region of interest. Results show an increase energy absorption in the desired region of interest inside a 8 cm object, when a higher absorption particle is present. With the use of multiple sources it is possible to photoactivate the drug while causing minimal damage to the surface of the radiated obje
ct.
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