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Authors: A. Lopes 1 ; A. Gabriel 1 ; J. Machado 1 ; P. Ribeiro 1 ; R. Gomes 2 ; João M. P. Coelho 2 ; C. O. Silva 3 ; C. P. Reis 4 ; J. P. Santos 1 and P. Vieira 1

Affiliations: 1 Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, Portugal ; 2 Faculdade de Ciências da Universidade de Lisboa, Portugal ; 3 Lusófona University, Portugal ; 4 Faculdade de Ciências da Universidade de Lisboa and Lusófona University, Portugal

ISBN: 978-989-758-170-0

Keyword(s): Near Infrared, Spectroscopy, GAMOS, Monte Carlo, Phototerapy, Breast Cancer.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Equipment ; Biomedical Instrumentation ; Biomedical Instruments and Devices ; Emerging Technologies ; Telecommunications ; Wireless and Mobile Technologies ; Wireless Information Networks and Systems

Abstract: Radiation therapy is one of many common treatments applied to breast cancer. Most usual radiation sources applied are ionizing radiation, such as g-rays and X-rays, and non-ionizing radiation such as ultraviolet radiation. The possibility of using near infrared light to photoactivate a drug inside an 8 cm diameter biological object is discussed in this work via Monte Carlo simulations. Two simulation setups performed in the Geant4/GAMOS framework are presented in order to study the viability of photoactivating a drug by using several near infrared light sources. The overall objective of this technique is to minimize energy concentrated at objects surface and maximize it in a predefined region of interest. Results show an increase energy absorption in the desired region of interest inside a 8 cm object, when a higher absorption particle is present. With the use of multiple sources it is possible to photoactivate the drug while causing minimal damage to the surface of the radiated objec t. (More)

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Paper citation in several formats:
Lopes, A.; Gabriel, A.; Machado, J.; Ribeiro, P.; Gomes, R.; Coelho, J.; Silva, C.; Reis, C.; Santos, J. and Vieira, P. (2016). Multiple Source Phototherapy in Breast Cancer: A Viability Study.In Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1 BIODEVICES: BIODEVICES, (BIOSTEC 2016) ISBN 978-989-758-170-0, pages 247-250. DOI: 10.5220/0005794902470250

@conference{biodevices16,
author={A. Lopes. and A. Gabriel. and J. Machado. and Ribeiro, P. and R. Gomes. and João M. P. Coelho. and C. O. Silva. and C. P. Reis. and J. P. Santos. and P. Vieira.},
title={Multiple Source Phototherapy in Breast Cancer: A Viability Study},
booktitle={Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1 BIODEVICES: BIODEVICES, (BIOSTEC 2016)},
year={2016},
pages={247-250},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005794902470250},
isbn={978-989-758-170-0},
}

TY - CONF

JO - Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1 BIODEVICES: BIODEVICES, (BIOSTEC 2016)
TI - Multiple Source Phototherapy in Breast Cancer: A Viability Study
SN - 978-989-758-170-0
AU - Lopes, A.
AU - Gabriel, A.
AU - Machado, J.
AU - Ribeiro, P.
AU - Gomes, R.
AU - Coelho, J.
AU - Silva, C.
AU - Reis, C.
AU - Santos, J.
AU - Vieira, P.
PY - 2016
SP - 247
EP - 250
DO - 10.5220/0005794902470250

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