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Authors: Bong-Kyu Choi 1 ; Suk Young Kim 2 and Sang-Hoon Rhee 1

Affiliations: 1 Seoul National University, Korea, Republic of ; 2 Yeungnam University, Korea, Republic of

Keyword(s): Composite, PLGA, Calcium Silicate, Pore, Bioactivity

Related Ontology Subjects/Areas/Topics: Biomaterials ; Biomedical Engineering ; Biomedical Instruments and Devices

Abstract: The PLGA/SiO2-CaO composite, which have a gradient pore structure, was newly prepared by the expansion of carbon dioxide gas in the PLGA matrix. The bioactive SiO2-CaO particles were made by a sol-gel method from tetraethyl orthosilicate and calcium nitrate tetrahydrate under acidic condition followed by the heat treatment at 600oC for 2 h. The PLGA/SiO2-CaO composite was then prepared by a solvent casting using chloroform as solvent. The composite was loaded into the high pressure chamber and then carbon dioxide gas was introduced achieving a final pressure of 10 MPa. After 3 days, the gas was released quickly and the gradient pore structure was developed. The samples were observed by FE-SEM and its bioactivity was tested in simulated body fluid.

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Paper citation in several formats:
Choi, B.; Young Kim, S. and Rhee, S. (2013). Preparation of a PLGA/Calcium Silicate Composite with Gradient Pore Structure. In Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2013) - BIODEVICES; ISBN 978-989-8565-34-1; ISSN 2184-4305, SciTePress, pages 239-242. DOI: 10.5220/0004200302390242

@conference{biodevices13,
author={Bong{-}Kyu Choi. and Suk {Young Kim}. and Sang{-}Hoon Rhee.},
title={Preparation of a PLGA/Calcium Silicate Composite with Gradient Pore Structure},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2013) - BIODEVICES},
year={2013},
pages={239-242},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004200302390242},
isbn={978-989-8565-34-1},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2013) - BIODEVICES
TI - Preparation of a PLGA/Calcium Silicate Composite with Gradient Pore Structure
SN - 978-989-8565-34-1
IS - 2184-4305
AU - Choi, B.
AU - Young Kim, S.
AU - Rhee, S.
PY - 2013
SP - 239
EP - 242
DO - 10.5220/0004200302390242
PB - SciTePress

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