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Authors: Carl Sandelius 1 ; 2 ; Athanasios Pappas 2 ; Arezoo Sarkheyli-Hägele 1 ; Andreas Heuer 2 and Magnus Johnsson 3

Affiliations: 1 Internet of Things and People Research Center, Department of Computer Science and Media Technology, Malmö University, Malmö, Sweden ; 2 Behavioural Neuroscience Laboratory, Department of Experimental Medical Sciences, Lund University, Lund, Sweden ; 3 Research Environment of Computer Science (RECS), Kristianstad University, Sweden

Keyword(s): Deep Learning, Machine Learning, Computer Vision, Behavioral Neuroscience, Pre-Clinical Rodent Models.

Abstract: We evaluate deep learning architectures for rat pose estimation using a six-camera system, focusing on ResNet and EfficientNet across various depths and augmentation techniques. Among the configurations tested, ResNet 152 with default augmentation provided the best performance when employing a multi-perspective network approach in the controlled experimental setup. It reached a Root Mean Squared Error (RMSE) of 8.74, 8.78, and 9.72 pixels for the different angles. The utilization of data augmentation revealed that less altering yields better performance. We propose potential areas for future research, including further refinement of model configurations, more in-depth investigation of inference speeds, and the possibility of transferring network weights to study other species, such as mice. The findings underscore the potential for deep learning solutions to advance preclinical research in behavioral neuroscience. We suggest building on this research to introduce behavioral recogniti on based on a 3D movement reconstruction, particularly emphasizing the motoric aspects of neurodegenerative diseases. This will allow for the correlation of observable behaviors with neuronal activity, contributing to a better understanding of the brain and aiding in developing new therapeutic strategies. (More)

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Paper citation in several formats:
Sandelius, C.; Pappas, A.; Sarkheyli-Hägele, A.; Heuer, A. and Johnsson, M. (2024). Leveraging Deep Learning for Approaching Automated Pre-Clinical Rodent Models. In Proceedings of the 16th International Joint Conference on Computational Intelligence - NCTA; ISBN 978-989-758-721-4; ISSN 2184-3236, SciTePress, pages 613-620. DOI: 10.5220/0013065600003837

@conference{ncta24,
author={Carl Sandelius. and Athanasios Pappas. and Arezoo Sarkheyli{-}Hägele. and Andreas Heuer. and Magnus Johnsson.},
title={Leveraging Deep Learning for Approaching Automated Pre-Clinical Rodent Models},
booktitle={Proceedings of the 16th International Joint Conference on Computational Intelligence - NCTA},
year={2024},
pages={613-620},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0013065600003837},
isbn={978-989-758-721-4},
issn={2184-3236},
}

TY - CONF

JO - Proceedings of the 16th International Joint Conference on Computational Intelligence - NCTA
TI - Leveraging Deep Learning for Approaching Automated Pre-Clinical Rodent Models
SN - 978-989-758-721-4
IS - 2184-3236
AU - Sandelius, C.
AU - Pappas, A.
AU - Sarkheyli-Hägele, A.
AU - Heuer, A.
AU - Johnsson, M.
PY - 2024
SP - 613
EP - 620
DO - 10.5220/0013065600003837
PB - SciTePress