loading
Papers Papers/2022 Papers Papers/2022

Research.Publish.Connect.

Paper

Paper Unlock

Authors: Peter Ulz 1 ; Michael R. Speicher 1 and Gerhard G. Thallinger 2

Affiliations: 1 Medical University Graz, Austria ; 2 Graz University of Technology, Austria

Keyword(s): Mitochondria, Next-generation Sequencing, Sequence Read Archive.

Abstract: The exponential growth of sequence databases in recent years opens up a lot of possibilities for reanalysis of public datasets. Here, we reanalyzed sequencing data from various experimental procedures to reconstruct the mitochondrial genome from sequence data of human samples. In a first step eight human cell lines were used to validate the approach and to ensure consistent genotype information across different library preparation techniques. Subsequently, 19,337 sequencing datasets were downloaded and checked for single-nucleotide variants and insertion or deletion events. We show that the mitochondrial genome can be inferred from many different library preparation techniques. We also generated reference mitochondrial genomes for eight cell lines. This approach may be used for sample identification as well as a general approach to study the mitochondrial genome from public sequencing data.

CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 18.191.238.128

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Ulz, P.; Speicher, M. and Thallinger, G. (2017). Reconstruction of Mitochondrial Genotypes from Diverse next Generation Sequencing Datasets. In Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2017) - BIOINFORMATICS; ISBN 978-989-758-214-1; ISSN 2184-4305, SciTePress, pages 29-36. DOI: 10.5220/0006110200290036

@conference{bioinformatics17,
author={Peter Ulz. and Michael R. Speicher. and Gerhard G. Thallinger.},
title={Reconstruction of Mitochondrial Genotypes from Diverse next Generation Sequencing Datasets},
booktitle={Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2017) - BIOINFORMATICS},
year={2017},
pages={29-36},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006110200290036},
isbn={978-989-758-214-1},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2017) - BIOINFORMATICS
TI - Reconstruction of Mitochondrial Genotypes from Diverse next Generation Sequencing Datasets
SN - 978-989-758-214-1
IS - 2184-4305
AU - Ulz, P.
AU - Speicher, M.
AU - Thallinger, G.
PY - 2017
SP - 29
EP - 36
DO - 10.5220/0006110200290036
PB - SciTePress

- Science and Technology Publications, Lda.
RESOURCES

Proceedings

Papers

Authors

Ontology

CONTACTS

Science and Technology Publications, Lda
Avenida de S. Francisco Xavier, Lote 7 Cv. C,
2900-616 Setúbal, Portugal.

Phone: +351 265 520 185 (National fixed network call)
Fax: +351 265 520 186
Email: info@scitepress.org

EXTERNAL LINKS

PRIMORIS

INSTICC

SCITEVENTS

CROSSREF

PROCEEDINGS SUBMITTED FOR INDEXATION BY:

dblp

Ei Compendex

SCOPUS

Semantic Scholar

Google Scholar

Microsoft Academic