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Authors: J. G. Rocha 1 ; V. Correia 1 ; J. L. Gomez Ribelles 2 ; S. Lanceros-Mendez 1 and A. Pitaes 1

Affiliations: 1 University of Minho, Portugal ; 2 Centro de Biomateriales, Universidad Politécnica de Valencia; Regenerative Medicine Unit, Centro de Investigación Príncipe Felipe; CIBER en Bioingeniería, Biomateriales y Nanomedicina, Spain

Keyword(s): Bioreactor control, Cell cultivation, Three-dimensional scaffold.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Instrumentation ; Biomedical Instruments and Devices ; Biomedical Sensors ; Transducers and Packaging

Abstract: Mechanical stimulation plays an important role in improving cell growth in the skeletal system, for example. In this article we describe a bioreactor in which cells in a three-dimensional scaffolds are stimulated by cyclically applied mechanical loads. The objective of this study is to develop a custom-designed bioreactor capable of applying controlled compressive loads to a cell-encapsulating scaffold. Its working principle is based on an innovative design of a feedback controlled electromagnetic actuator, which allows the application of compressive forces to the samples and at the same time, it allows the measurement of the produced displacement.

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Paper citation in several formats:
Rocha, J. ; Correia, V. ; Gomez Ribelles, J. ; Lanceros-Mendez, S. and Pitaes, A. (2010). BIOREACTOR FOR MECHANICAL CELL STIMULATION - Concept and Design. In Proceedings of the Third International Conference on Biomedical Electronics and Devices (BIOSTEC 2010) - BIODEVICES; ISBN 978-989-674-017-7; ISSN 2184-4305, SciTePress, pages 147-151. DOI: 10.5220/0002759401470151

@conference{biodevices10,
author={J. G. Rocha and V. Correia and J. L. {Gomez Ribelles} and S. Lanceros{-}Mendez and A. Pitaes},
title={BIOREACTOR FOR MECHANICAL CELL STIMULATION - Concept and Design},
booktitle={Proceedings of the Third International Conference on Biomedical Electronics and Devices (BIOSTEC 2010) - BIODEVICES},
year={2010},
pages={147-151},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002759401470151},
isbn={978-989-674-017-7},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the Third International Conference on Biomedical Electronics and Devices (BIOSTEC 2010) - BIODEVICES
TI - BIOREACTOR FOR MECHANICAL CELL STIMULATION - Concept and Design
SN - 978-989-674-017-7
IS - 2184-4305
AU - Rocha, J.
AU - Correia, V.
AU - Gomez Ribelles, J.
AU - Lanceros-Mendez, S.
AU - Pitaes, A.
PY - 2010
SP - 147
EP - 151
DO - 10.5220/0002759401470151
PB - SciTePress