Automatic Computation of Biophysical Cell Parameters in Digital Holographic Microscopy Images

Lilith Brandt; Klaus Brinker; Björn Kemper

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Paper

Automatic Computation of Biophysical Cell Parameters in Digital Holographic Microscopy Images

Topics: Medical Informatics; Pattern Recognition and Machine Learning

In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: BIOSTEC, 431-437, 2018 , Funchal, Madeira, Portugal

Authors: Lilith Brandt ¹ ; Klaus Brinker ¹ and Björn Kemper ²

Affiliations: ¹ Hamm-Lippstadt University of Applied Sciences, Germany ; ² University of Münster, Germany

Keyword(s): Computer Vision, Segmentation, Region Detection, Digital Holographic Microscopy, Quantitative Phase Imaging, Automatic Cell Detection.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Health Information Systems ; Pattern Recognition and Machine Learning

Abstract: This paper presents an analysis pipeline for automatically detecting cells in digitally reconstructed quantitative phase images acquired by digital holographic microscopy and for computing biophysical cell parameters. Using an intelligent, integrated image analysis approach, we optimize the overall analysis process which includes several time-consuming, manual steps. The proposed automatic approach shows promising results in an experimental comparison with the current manual evaluation process.

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Paper citation in several formats:

Brandt, L., Brinker, K. and Kemper, B. (2018). Automatic Computation of Biophysical Cell Parameters in Digital Holographic Microscopy Images . In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - HEALTHINF; ISBN 978-989-758-281-3; ISSN 2184-4305, SciTePress, pages 431-437. DOI: 10.5220/0006585504310437

@conference{healthinf18,
author={Lilith Brandt and Klaus Brinker and Björn Kemper},
title={Automatic Computation of Biophysical Cell Parameters in Digital Holographic Microscopy Images },
booktitle={Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - HEALTHINF},
year={2018},
pages={431-437},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006585504310437},
isbn={978-989-758-281-3},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2018) - HEALTHINF
TI - Automatic Computation of Biophysical Cell Parameters in Digital Holographic Microscopy Images
SN - 978-989-758-281-3
IS - 2184-4305
AU - Brandt, L.
AU - Brinker, K.
AU - Kemper, B.
PY - 2018
SP - 431
EP - 437
DO - 10.5220/0006585504310437
PB - SciTePress