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Authors: F. Poulon 1 ; F. Jamme 2 ; A. Ibrahim 1 ; C. Métais 1 ; P. Varlet 3 ; M. Juchaux 1 ; B. Devaux 4 ; M. Refregiers 2 and D. Abi Haidar 5

Affiliations: 1 IMNC Laboratory, UMR 8165-CNRS/ IN2P3 and Paris-Saclay University, France ; 2 DISCO beamline and Synchrotron SOLEIL, France ; 3 Sainte-Anne Hospital and Paris Descartes University, France ; 4 Sainte Anne-Hospital and Paris Descartes University, France ; 5 IMNC Laboratory, UMR 8165-CNRS/ IN2P3, Paris-Saclay University, Paris Diderot University and Sorbonne Paris Cité, France

Keyword(s): Endomicroscopy, Brain Tumours, Deep UV, Synchrotron SOLEIL, Spectroscopy, Wide-field Imaging.

Related Ontology Subjects/Areas/Topics: Biomedical Optics ; Optics ; Photonics, Optics and Laser Technology ; Spectroscopy, Imaging and Metrology

Abstract: In order to build a multimodal nonlinear endomicroscope to image brain border during operation, our group is building an optical database on brain biopsy tissues analysis collected with excitation panning from deep UV to near infrared. This paper focuses on the results from deep UV excitation of endogenous fluorescence from glioblastoma and control human brain samples. The samples were imaged and spectrally analysed. The excitation wavelengths were tuned from 275 nm to 340 nm. Two promising indicators to discriminate tumorous tissue from the control were found. A preliminary correspondence between fluorescence images and histological H&E staining open a huge door to confirm results with a medical expertise.

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Paper citation in several formats:
Poulon, F.; Jamme, F.; Ibrahim, A.; Métais, C.; Varlet, P.; Juchaux, M.; Devaux, B.; Refregiers, M. and Abi Haidar, D. (2017). Endogenous Fluorescence Analysis under Deep UV Excitation to Discriminate Human Brain Tumor Tissue - Difference between Glioblastoma and Healthy Control Tissue. In Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology - PHOTOPTICS; ISBN 978-989-758-223-3; ISSN 2184-4364, SciTePress, pages 152-157. DOI: 10.5220/0006103601520157

@conference{photoptics17,
author={F. Poulon. and F. Jamme. and A. Ibrahim. and C. Métais. and P. Varlet. and M. Juchaux. and B. Devaux. and M. Refregiers. and D. {Abi Haidar}.},
title={Endogenous Fluorescence Analysis under Deep UV Excitation to Discriminate Human Brain Tumor Tissue - Difference between Glioblastoma and Healthy Control Tissue},
booktitle={Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology - PHOTOPTICS},
year={2017},
pages={152-157},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006103601520157},
isbn={978-989-758-223-3},
issn={2184-4364},
}

TY - CONF

JO - Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology - PHOTOPTICS
TI - Endogenous Fluorescence Analysis under Deep UV Excitation to Discriminate Human Brain Tumor Tissue - Difference between Glioblastoma and Healthy Control Tissue
SN - 978-989-758-223-3
IS - 2184-4364
AU - Poulon, F.
AU - Jamme, F.
AU - Ibrahim, A.
AU - Métais, C.
AU - Varlet, P.
AU - Juchaux, M.
AU - Devaux, B.
AU - Refregiers, M.
AU - Abi Haidar, D.
PY - 2017
SP - 152
EP - 157
DO - 10.5220/0006103601520157
PB - SciTePress

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