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Authors: Yariv Z. Levy 1 ; Dino Levy 2 ; Jerrold S. Meyer 1 and Hava T. Siegelmann 1

Affiliations: 1 University of Massachusetts Amherst, United States ; 2 The Weizmann Institute of Science, Israel

ISBN: 978-989-8111-65-4

Keyword(s): Addiction, Multiscale Modeling, Bio-signal Modeling, Behavioral Processes, Cognitive Processes, Neurophysiological Processes.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Signal Processing ; Physiological Processes and Bio-Signal Modeling, Non-Linear Dynamics

Abstract: According to the United Nations, approximately 24.7 million people used amphetamines, 16 million used cocaine, and 12 million used heroin in 2006/07 (Costa, 2008). Full recovery from drug addiction by chemical treatment and/or social and psychological support is uncertain. The present investigation was undertaken to expand our understanding of the factors that drive the dynamics of addiction. A new multiscale computational model is presented which integrates current theories of addiction, unlike previous models, considers addiction as a reversible process (Siegelmann, 2008). Explicit time dependency is added to the inhibition and the compulsion processes. Preliminary computational predictions of drug-seeking behavior are presented and potential correlation with experimental data is discussed. Validation of the model appears promising, however additional investigation is required.

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Paper citation in several formats:
Levy Y.; Levy D.; Meyer J.; T. Siegelmann H. and (2009). DRUG ADDICTION: A COMPUTATIONAL MULTISCALE MODEL COMBINING NEUROPSYCHOLOGY, COGNITION AND BEHAVIOR.In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2009) ISBN 978-989-8111-65-4, pages 87-94. DOI: 10.5220/0001539100870094

@conference{biosignals09,
author={Yariv Z. Levy and Dino Levy and Jerrold S. Meyer and Hava {T. Siegelmann}},
title={DRUG ADDICTION: A COMPUTATIONAL MULTISCALE MODEL COMBINING NEUROPSYCHOLOGY, COGNITION AND BEHAVIOR},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2009)},
year={2009},
pages={87-94},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001539100870094},
isbn={978-989-8111-65-4},
}

TY - CONF

JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2009)
TI - DRUG ADDICTION: A COMPUTATIONAL MULTISCALE MODEL COMBINING NEUROPSYCHOLOGY, COGNITION AND BEHAVIOR
SN - 978-989-8111-65-4
AU - Levy, Y.
AU - Levy, D.
AU - Meyer, J.
AU - T. Siegelmann, H.
PY - 2009
SP - 87
EP - 94
DO - 10.5220/0001539100870094

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