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Authors: Ibrahim Chegrane ; Athman Sighier ; Chahrazed Ighilaza and Aicha Boutorh

Affiliation: USTHB, Algeria

Keyword(s): Bioinformatics, Multiple Alignment, DIALIGN, Diagonals Consistency.

Related Ontology Subjects/Areas/Topics: Algorithms and Software Tools ; Bioinformatics ; Biomedical Engineering ; Genomics and Proteomics ; Sequence Analysis

Abstract: DIALIGN is a well known Algorithm for pairwise as well as multiple alignment of nucleic acid and protein sequences. It combines local and global alignment features. In this paper we present a new method to better solve the problem of diagonals consistency in DIALIGN algorithm using graph theory modeling. and we describe a new implementation of the method from the extraction of diagonals to the final alignment process. We show the power of our proposed aproach by comparing it with DIALIGN 2.2 using benchmarks from ”BAliBASE” and ”SMART” databases.

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Paper citation in several formats:
Chegrane, I.; Sighier, A.; Ighilaza, C. and Boutorh, A. (2015). Diagonal Consistency Problem Resolution in DIALIGN Algorithm. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2015) - BIOINFORMATICS; ISBN 978-989-758-070-3; ISSN 2184-4305, SciTePress, pages 225-231. DOI: 10.5220/0005284802250231

@conference{bioinformatics15,
author={Ibrahim Chegrane. and Athman Sighier. and Chahrazed Ighilaza. and Aicha Boutorh.},
title={Diagonal Consistency Problem Resolution in DIALIGN Algorithm},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2015) - BIOINFORMATICS},
year={2015},
pages={225-231},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005284802250231},
isbn={978-989-758-070-3},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2015) - BIOINFORMATICS
TI - Diagonal Consistency Problem Resolution in DIALIGN Algorithm
SN - 978-989-758-070-3
IS - 2184-4305
AU - Chegrane, I.
AU - Sighier, A.
AU - Ighilaza, C.
AU - Boutorh, A.
PY - 2015
SP - 225
EP - 231
DO - 10.5220/0005284802250231
PB - SciTePress