Authors:
Dongxuan Bao
1
;
Zhuo Zou
2
;
Yuxiang Huan
1
;
Chuanying Zhai
2
;
Tiberiu Bagaian
3
;
Hannu Tenhunen
2
;
Bengt Källbäck
3
and
Li-Rong Zheng
4
Affiliations:
1
Fudan University, China
;
2
KTH-Royal Institute of Technology, Sweden
;
3
CathPrint AB, Sweden
;
4
Fudan University and KTH-Royal Institute of Technology, China
Keyword(s):
Smart Catheter, TBI, Real-Time Monitoring, Pressure, Temperature.
Related
Ontology
Subjects/Areas/Topics:
Biomedical Engineering
;
Biomedical Instrumentation
;
Biomedical Instruments and Devices
;
Biomedical Sensors
;
Devices
;
Health Monitoring Devices
;
Human-Computer Interaction
;
Physiological Computing Systems
Abstract:
This paper demonstrates a smart catheter system with intracranial pressure (ICP) and temperature sensing capability which is designed for real-time monitoring in traumatic brain injury (TBI) therapy. It uses a single flexible catheter with a 1 mm (3 Fr) diameter that integrates electrodes and sophisticated silicon chip on flexible substrates, enabling multimodality monitoring of physiological signals.
A micro-electro-mechanical-system (MEMS) catheter pressure sensor is mounted on the distal end. It can be used for detecting both pressure and temperature by different switch configurations, which minimizes the size of catheter and reduces the cost. The interconnects (signalling conductors) are printed on a bio-compatible flexible substrate, and the sensor is interfaced with an embedded electronic system
at the far-end. The electronic system consists of analog front end with analog-to-digital converter (ADC), a microcontroller, and data interface to the hospital infrastructure with
a graphical user interface (GUI). The overall smart catheter system achieves a pressure sensing root mean square error (RMSE) of +-1.5 mmHg measured from 20 mmHg to 300 mmHg above 1 atm and
a temperature sensing RMSE of +-0.08 ºC measured from 32 ºC to 42 ºC. The sampling rate can be up to 10S/s. The in vivo performance is demonstrated in laboratory animals.
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