loading
Papers

Research.Publish.Connect.

Paper

Paper Unlock

Authors: T. Pinheiro 1 ; C. Ramos 1 ; P. Napoleão 2 ; C. Mendonça 1 ; C. Fondinho 3 ; M. Selas 3 ; M. Mota Carmo 4 and R. Cruz Ferreira 4

Affiliations: 1 Universidade Técnica de Lisboa, Portugal ; 2 Instituto de Medicina Molecular, Portugal ; 3 Hospital de Santa Marta CHLC, Portugal ; 4 Hospital de Santa Marta CHLC and Universidade Nova de Lisboa, Portugal

ISBN: 978-989-8565-78-5

Keyword(s): Coronary Artery Disease, Atherosclerosis, Vulnerable Plaque Phenotype.

Abstract: The relationship between plaque morphology and clinical presentation was examined. Lumen dimensions, atheroma morphology and composition were assessed by virtual histology intravascular ultrasound (VH-IVUS) in 1757 frames of coronary segments of interest of 17 patients with acute and chronic coronary artery disease, i.e., ST-elevation (STEMI) and non-ST-elevation (NSTEMI) myocardial infarction, unstable angina (UA) and stable angina (SA). Large plaque areas with distended elastic lamina (EEL), rich in fibrotic (FB) and fibro-fatty (FF) tissues associated with STEMI and UA. Variants of this phenotype consisting of large calcium deposits and reduced lumen area were prevalent in NSTEMI patients. SA patients consistently showed plaques with small areas, marked constrictive growth and low FF content. IVUS-derived plaque measures provided phenotypes of vulnerability and rupture that may help improving risk stratification of both symptomatic and asymptomatic patients.

PDF ImageFull Text

Download
CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 3.95.131.208

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Pinheiro, T.; Ramos, C.; Napoleão, P.; Mendonça, C.; Fondinho, C.; Selas, M.; Mota Carmo, M. and Cruz Ferreira, R. (2013). Plaque Vulnerability Phenotype in Patients with Coronary Artery Disease - An Intravascular Ultrasound Radiofrequency Analysis.In Proceedings of the International Congress on Cardiovascular Technologies - Volume 1: VisualCardio, (CARDIOTECHNIX 2013) ISBN 978-989-8565-78-5, pages 84-89. DOI: 10.5220/0004664400840089

@conference{visualcardio13,
author={T. Pinheiro. and C. Ramos. and P. Napoleão. and C. Mendon\c{C}a. and C. Fondinho. and M. Selas. and M. Mota Carmo. and R. Cruz Ferreira.},
title={Plaque Vulnerability Phenotype in Patients with Coronary Artery Disease - An Intravascular Ultrasound Radiofrequency Analysis},
booktitle={Proceedings of the International Congress on Cardiovascular Technologies - Volume 1: VisualCardio, (CARDIOTECHNIX 2013)},
year={2013},
pages={84-89},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004664400840089},
isbn={978-989-8565-78-5},
}

TY - CONF

JO - Proceedings of the International Congress on Cardiovascular Technologies - Volume 1: VisualCardio, (CARDIOTECHNIX 2013)
TI - Plaque Vulnerability Phenotype in Patients with Coronary Artery Disease - An Intravascular Ultrasound Radiofrequency Analysis
SN - 978-989-8565-78-5
AU - Pinheiro, T.
AU - Ramos, C.
AU - Napoleão, P.
AU - Mendonça, C.
AU - Fondinho, C.
AU - Selas, M.
AU - Mota Carmo, M.
AU - Cruz Ferreira, R.
PY - 2013
SP - 84
EP - 89
DO - 10.5220/0004664400840089

Login or register to post comments.

Comments on this Paper: Be the first to review this paper.