Authors:
Ioana Nica
1
;
Marjolijn Deprez
1
;
Frederik Ceyssens
1
;
Kris van Kuyck
1
;
Robert Puers
1
;
Bart Nuttin
2
and
Jean-Marie Aerts
1
Affiliations:
1
KU Leuven, Belgium
;
2
KU Leuven and University Hospitals Leuven, Belgium
Keyword(s):
Beta Oscillations, Frequency Modulations, Local Field Potential, Motor Cortex, Rehabilitation, Brain Lesion, Gait.
Related
Ontology
Subjects/Areas/Topics:
Applications and Services
;
Biomedical Engineering
;
Biomedical Signal Processing
;
Computer Vision, Visualization and Computer Graphics
;
Medical Image Detection, Acquisition, Analysis and Processing
;
Real-Time Systems
Abstract:
Oscillatory neural activity was reported to have various physiological roles in information processing of
brain functions. It is now established that extracellular activity in the motor cortex encodes aspects of
movement, involving planning and motor control. Oscillatory patterns have also been hypothesized to play a
role in brain recovery and functional remapping. In this study, we measured neural activity from within the
cavity wall of a motor cortex lesion, in a rat model, while the animals performed a skilled walking task. We
aim at providing a possible framework of analysis, focused on revealing oscillatory patterns in the cavity
wall and their correlation with motor deficits, by using a combination of spectral features, involving power
spectra and coherence estimates in the beta and gamma frequency bands.