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Authors: Rastita Widyasari ; Iswan Abbas Nusi ; Poernomo Boedi Setiawan ; Herry Purbayu ; Titong Sugihartono ; Ummi Maimunah ; Ulfa Kholili ; Budi Widodo ; Amie Vidyani ; Muhammad Miftahussurur and Husin Thamrin

Affiliation: Department of Internal Medicine, Faculty of medicine Universitas Airlangga, Dr. Soetomo General Hospital and Surabaya, Indonesia

Keyword(s): Irritable bowel syndrome, bowel habit, barrier, genetic, brain-gut axis

Abstract: Irritable bowel syndrome (IBS) is a large bowel functional disorder characterized by abdominal pain or discomfort and is associated with bowel habit changes without organic disorder. IBS is affected by many factors and is suspected of involving central and peripheral mechanisms, such as gastrointestinal dysmotility, bowel visceral/mucosal hypersensitivity, increased bowel permeability and interaction among the luminal factors including food and bowel microbiota changes, bowel epithelial barrier, mucosa immunity, genetic factor and biopsychosocial and brain gut axis which are suspected to affect IBS pathophysiology. Understanding the various factors and mechanisms underlying IBS helps in the consideration of management and repair of patients’ prognosis

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Paper citation in several formats:
Widyasari, R.; Nusi, I.; Setiawan, P.; Purbayu, H.; Sugihartono, T.; Maimunah, U.; Kholili, U.; Widodo, B.; Vidyani, A.; Miftahussurur, M. and Thamrin, H. (2018). Pathophysiology of Irritable Bowel Syndrome. In Proceedings of Surabaya International Physiology Seminar - SIPS; ISBN 978-989-758-340-7; ISSN 2184-3678, SciTePress, pages 470-476. DOI: 10.5220/0007340704700476

@conference{sips18,
author={Rastita Widyasari. and Iswan Abbas Nusi. and Poernomo Boedi Setiawan. and Herry Purbayu. and Titong Sugihartono. and Ummi Maimunah. and Ulfa Kholili. and Budi Widodo. and Amie Vidyani. and Muhammad Miftahussurur. and Husin Thamrin.},
title={Pathophysiology of Irritable Bowel Syndrome},
booktitle={Proceedings of Surabaya International Physiology Seminar - SIPS},
year={2018},
pages={470-476},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007340704700476},
isbn={978-989-758-340-7},
issn={2184-3678},
}

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - SIPS
TI - Pathophysiology of Irritable Bowel Syndrome
SN - 978-989-758-340-7
IS - 2184-3678
AU - Widyasari, R.
AU - Nusi, I.
AU - Setiawan, P.
AU - Purbayu, H.
AU - Sugihartono, T.
AU - Maimunah, U.
AU - Kholili, U.
AU - Widodo, B.
AU - Vidyani, A.
AU - Miftahussurur, M.
AU - Thamrin, H.
PY - 2018
SP - 470
EP - 476
DO - 10.5220/0007340704700476
PB - SciTePress

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