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Authors: Luna Dimitrio 1 ; Roberto Natalini 2 and Luciano Milanesi 2

Affiliations: 1 Università degli Studi “La Sapienza” di Roma and inria rocquencourt, Italy ; 2 Consiglio Nazionale delle Ricerche, Italy

Keyword(s): Cytoplasmic enhanced transport, Microtubules, Partial differential models.

Related Ontology Subjects/Areas/Topics: Agents ; Artificial Intelligence ; Bioinformatics ; Biomedical Engineering ; Computational Molecular Systems ; Enterprise Information Systems ; Information Systems Analysis and Specification ; Methodologies and Technologies ; Operational Research ; Simulation ; Systems Biology

Abstract: We consider a simple model for signal transport in the cytoplasm. Following some recent experimental evidences, the standard diffusion model is supplemented by advection operated through an attachement/detachement mechanism along microtubules. This model is given by a system of partial differential equations which are cast in different dimensions and connected by suitable exchange rules. A numerical scheme is introduced and some simulations are presented and discussed to show the performances of our model.

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Paper citation in several formats:
Dimitrio, L.; Natalini, R. and Milanesi, L. (2011). A MATHEMATICAL MODEL FOR THE ENHANCED CYTOPLASMIC TRANSPORT - How to Get (Faster) to the Nucleus. In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2011) - BIOINFORMATICS; ISBN 978-989-8425-36-2; ISSN 2184-4305, SciTePress, pages 39-46. DOI: 10.5220/0003135700390046

@conference{bioinformatics11,
author={Luna Dimitrio. and Roberto Natalini. and Luciano Milanesi.},
title={A MATHEMATICAL MODEL FOR THE ENHANCED CYTOPLASMIC TRANSPORT - How to Get (Faster) to the Nucleus},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2011) - BIOINFORMATICS},
year={2011},
pages={39-46},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003135700390046},
isbn={978-989-8425-36-2},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOSTEC 2011) - BIOINFORMATICS
TI - A MATHEMATICAL MODEL FOR THE ENHANCED CYTOPLASMIC TRANSPORT - How to Get (Faster) to the Nucleus
SN - 978-989-8425-36-2
IS - 2184-4305
AU - Dimitrio, L.
AU - Natalini, R.
AU - Milanesi, L.
PY - 2011
SP - 39
EP - 46
DO - 10.5220/0003135700390046
PB - SciTePress

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