Authors:
Juan José Fuertes
1
;
Valery Naranjo
1
;
Pablo González
1
;
Ángela Bernabeu
2
;
Mariano Alcañiz
3
and
Javier Sanchez
4
Affiliations:
1
Universitat Politècnica de València and I3BH/LabHuman, Spain
;
2
Inscanner S.L., Spain
;
3
Universitat Politècnica de València, I3BH/LabHuman and Instituto de Salud Carlos III, Spain
;
4
Philips Healthcare España, Spain
Keyword(s):
Magnetic Resonance Spectroscopy, Brain Cancer Detection, Multivoxel, Magnetic Resonance Imaging, Neuronavigator.
Related
Ontology
Subjects/Areas/Topics:
Biomedical Engineering
;
Biomedical Instruments and Devices
;
Brain-Computer Interfaces
;
Computer-Aided Detection and Diagnosis
;
Devices
;
Human-Computer Interaction
;
Imaging and Visualization Devices
;
Physiological Computing Systems
;
Spectroscopic Applications
Abstract:
This work presents a simple and interactive spectroscopic tool to help clinicians for brain cancer detection. Firstly, Magnetic Resonance Spectroscopy (MRS) and Magnetic Resonance Imaging (MRI) are registered to perform brain analysis. After processing the spectroscopic signals with HLSVD method for water suppression, zero-filling and phase-correction algorithms, and apodization functions to improve the signal-to-noise ratio (SNR), the metabolite brain maps are generated in order to analyze brain composition. A 3D-spatial distribution of the anatomical and spectroscopic images and how they are registered are presented to facilitate surgery planning. The goal is to generate metabolite brain maps which can be merged with anatomical images in the neuronavigator to provide the surgeon with the exact point where performing the biopsy.