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Authors: François-Benoit Vialatte 1 ; Charles François Vincent Latchoumane 2 ; Nigel Hudson 3 ; Sunil Wimalaratna 4 ; Jordi Solé-Casals 5 ; Jaeseung Jeong 2 and Andrzej Cichocki 1

Affiliations: 1 Riken BSI, Japan ; 2 KAIST, Korea, Republic of ; 3 Derriford Hospital, United Kingdom ; 4 Radcliffe Infirmary, United Kingdom ; 5 University of Vic, Spain

Keyword(s): EEG, Alzheimer, time-frequency, bump, local synchrony

Abstract: We explore the potential of bump modeling to extract transient local synchrony in EEG, as a marker for mildAD (mild Alzheimer’s disease). EEG signals of patients with mildAD are transformed to a wavelet timefrequency representation, and afterwards a sparsification process (bump modeling) extracts time-frequency oscillatory bursts. We observed that organized oscillatory events contain stronger discriminative signatures than averaged spectral EEG statistics for patients in a probable early stage of Alzheimer’s disease. Specifically, bump modeling enhanced the difference between mildAD patients and age-matched control subjects in the θ and β frequency ranges.This effect is consistent with previous results obtained on other databases.

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Paper citation in several formats:
Vialatte, F.; François Vincent Latchoumane, C.; Hudson, N.; Wimalaratna, S.; Solé-Casals, J.; Jeong, J. and Cichocki, A. (2010). SPARSE BUMP MODELING OF MILDAD PATIENTS - Modeling Transient Oscillations in the EEG of Patients with Mild Alzheimer’s Disease. In Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2010) - Special Session on Neural Signals of Brain Disorde; ISBN 978-989-674-018-4; ISSN 2184-4305, SciTePress, pages 479-484. DOI: 10.5220/0002755104790484

@conference{special session on neural signals of brain disorde10,
author={Fran\c{C}ois{-}Benoit Vialatte. and Charles {Fran\c{C}ois Vincent Latchoumane}. and Nigel Hudson. and Sunil Wimalaratna. and Jordi Solé{-}Casals. and Jaeseung Jeong. and Andrzej Cichocki.},
title={SPARSE BUMP MODELING OF MILDAD PATIENTS - Modeling Transient Oscillations in the EEG of Patients with Mild Alzheimer’s Disease},
booktitle={Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2010) - Special Session on Neural Signals of Brain Disorde},
year={2010},
pages={479-484},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002755104790484},
isbn={978-989-674-018-4},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the Third International Conference on Bio-inspired Systems and Signal Processing (BIOSTEC 2010) - Special Session on Neural Signals of Brain Disorde
TI - SPARSE BUMP MODELING OF MILDAD PATIENTS - Modeling Transient Oscillations in the EEG of Patients with Mild Alzheimer’s Disease
SN - 978-989-674-018-4
IS - 2184-4305
AU - Vialatte, F.
AU - François Vincent Latchoumane, C.
AU - Hudson, N.
AU - Wimalaratna, S.
AU - Solé-Casals, J.
AU - Jeong, J.
AU - Cichocki, A.
PY - 2010
SP - 479
EP - 484
DO - 10.5220/0002755104790484
PB - SciTePress