CHROMOSOME REGION RECOGNITION WITH LOCAL BAND PATTERNS
Toru Abe, Chieko Hamada, Tetsuo Kinoshita
2009
Abstract
To make the visual examination of a chromosome image for various chromosome abnormalities, individual chromosome regions have to be extracted from the subject image and classified into the distinct chromosome types. To improve the accuracy and flexibility in this process, we propose a subregion (local band pattern) based method for recognizing chromosome regions in the image. This method regards each chromosome region as a series of subregions, and iterates a search for subregions in the image consecutively. Consequently, chromosome region classification is performed simultaneously with its extraction for each subregion. Since the dimensions and intensities of chromosome regions vary with every image, effective subregion searches require templates whose dimensions and intensities correspond with those of chromosome regions in the image. To develop an effective subregion search, we also propose a method for adjusting the dimensions of templates to those of chromosome regions in the image and adapting the intensities in the image to those of the templates.
References
- Carothers, A. and Piper, J. (1994). Computer-aided classification of human chromosomes: a review. Statistics Computing, 4:161-171.
- Graham, J. and Piper, J. (1994). Automatic karyotype analysis. Meth. Mol. Biol., 29:141-185.
- Groen, F. C. A., ten Kate, T. K., Smeulders, A. W. M., and Young, I. T. (1989). Human chromosome classification based on local band descriptors. Pattern Recognit. Lett., 9:211-222.
- Harnden, D. G. and Klinger, H. P., editors (1985). ISCN1985: An international system for human cytogenetic nomenclature (1985). S. Karger AG.
- Moradi, M. and Setarehdan, S. K. (2006). New features for automatic classification of human chromosomes: a feasibility study. Pattern Recognit. Lett., 27:19-28.
- Piper, J. and Granum, E. (1989). On fully automatic feature measurement for banded chromosome classification. Cytometry, 10:242-255.
- Wu, Q., Liu, Z., Chen, T., Xiong, Z., and Castleman, K. R. (2005). Subspace-based prototyping and classification of chromosome images. IEEE Trans. Pattern Anal. Machine Intell., 14:1277-1287.
- ZooWeb (2003). - Karyotypes home page. http://worms. zoology.wisc.edu/zooweb/Phelps/karyotype.html.
Paper Citation
in Harvard Style
Abe T., Hamada C. and Kinoshita T. (2009). CHROMOSOME REGION RECOGNITION WITH LOCAL BAND PATTERNS . In Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2009) ISBN 978-989-8111-65-4, pages 49-56. DOI: 10.5220/0001534500490056
in Bibtex Style
@conference{biosignals09,
author={Toru Abe and Chieko Hamada and Tetsuo Kinoshita},
title={CHROMOSOME REGION RECOGNITION WITH LOCAL BAND PATTERNS},
booktitle={Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2009)},
year={2009},
pages={49-56},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001534500490056},
isbn={978-989-8111-65-4},
}
in EndNote Style
TY - CONF
JO - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing - Volume 1: BIOSIGNALS, (BIOSTEC 2009)
TI - CHROMOSOME REGION RECOGNITION WITH LOCAL BAND PATTERNS
SN - 978-989-8111-65-4
AU - Abe T.
AU - Hamada C.
AU - Kinoshita T.
PY - 2009
SP - 49
EP - 56
DO - 10.5220/0001534500490056