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much greater number of equations and variables.
Our aim is to extend our investigations to more
complex reactions, governing the cell function-
ing. In fact, it is well known that the mathe-
matical description of the double phosphorylation–
dephosphorylation mechanism is a common feature
not only of the MAPK but of any reaction involving a
double-step activation and the corresponding double-
step deactivation. Even if we expect, in general, much
more involved phenomena, we think that our mathe-
matical tools will be able to model, explain and pre-
dict their main characteristics.
The results that we present in this paper do need,
of course, a validation through experimental data. For
this purpose, we have got off the ground a collabora-
tion with personnel from ISMAC–CNR, the Institute
for Macromolecular studies (Genova,Italy), in order
to test our predictions.
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