STATISTICAL MECHANICS OF PROTEINS IN THE RANDOM COIL STATE

Cigdem Sevim Bayrak, Burak Erman

2012

Abstract

Denatured proteins are mostly partially folded and compact proteins. A statistical analysis on thermodynamic properties is presented to describe and characterize denatured proteins. Conformational free energy, energy, entropy and heat capacity expressions are derived using the Rotational Isomeric States model of polymer theory. The state space and the probabilities of each state are comprised from a coil database. Properties for the denatured state are obtained for a sample set of proteins taken from the Protein Data Bank. Thermodynamic expressions of denatured state are derived.

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Paper Citation


in Harvard Style

Sevim Bayrak C. and Erman B. (2012). STATISTICAL MECHANICS OF PROTEINS IN THE RANDOM COIL STATE . In Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012) ISBN 978-989-8425-90-4, pages 220-225. DOI: 10.5220/0003785202200225


in Bibtex Style

@conference{bioinformatics12,
author={Cigdem Sevim Bayrak and Burak Erman},
title={STATISTICAL MECHANICS OF PROTEINS IN THE RANDOM COIL STATE},
booktitle={Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012)},
year={2012},
pages={220-225},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003785202200225},
isbn={978-989-8425-90-4},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms - Volume 1: BIOINFORMATICS, (BIOSTEC 2012)
TI - STATISTICAL MECHANICS OF PROTEINS IN THE RANDOM COIL STATE
SN - 978-989-8425-90-4
AU - Sevim Bayrak C.
AU - Erman B.
PY - 2012
SP - 220
EP - 225
DO - 10.5220/0003785202200225