AN IMMERSIVE VIRTUAL ENVIRONMENT FOR PHANTOM LIMB PAIN REHABILITATION
Steve Pettifer, Toby Howard, Ben Blundell, David Edwards, Ilan Lieberman
2012
Abstract
Phantom Limb Pain is a debilitating condition that affects a significant percentage of patients after loss of an arm or leg. These patients experience chronic pain and other unpleasant sensations in the missing limb, and the pain resists treatment. Previous research has demonstrated that pain levels can be reduced in some patients when they are immersed in a virtual environment that presents a 3D computer graphics visualisation of their missing limb, the movements of which are controlled by sensors attached to the remaining limb. In this paper we describe a novel approach to the implementation of such a system, using the Kinect game device for limb motion tracking, in conjunction with wireless motion sensors worn by the patient. We present some preliminary, but very encouraging, results based on an informal trial with a patient.
References
- Anderson-Barnes, V. C., McAuliffe, C., Swanberg, K. M., and Tsao, J. W. (2009). Phantom limb pain-a phenomenon of proprioceptive memory? Med. Hypotheses, 73:555-558.
- Black, L. M., Persons, R. K., and Jamieson, B. (2009). Clinical inquiries. What is the best way to manage phantom limb pain? J Fam Pract, 58:155-158.
- Bone, M., Critchley, P., and Buggy, D. J. (2002).
- Gabapentin in postamputation phantom limb pain: a randomized, double-blind, placebo-controlled, crossover study. Reg Anesth Pain Med, 27:481-486.
- Borsook, D., Becerra, L., Fishman, S., Edwards, A., Jennings, C. L., Stojanovic, M., Papinicolas, L., Ramachandran, V. S., Gonzalez, R. G., and Breiter, H. (1998). Acute plasticity in the human somatosensory cortex following amputation. Neuroreport, 9:1013- 1017.
- Bowsher, D., Rigge, M., and Sopp, L. (1991). Prevalence of chronic pain in the british population: A telephone survey of 1037 households. Pain Clinic, 4:223-230.
- Brodie, E. E., Whyte, A., and Waller, B. (2003). Increased motor control of a phantom leg in humans results from the visual feedback of a virtual leg. Neurosci Letters, 2(341):167-169.
- Calderwood, M. D., Kelly, J., McNamara, T. P., and Bodenheimer, B. (2009). Adding head tracking to desktop virtual reality with the wii remote as an aid to spatial cognition. In Proceedings of the 6th Symposium on Applied Perception in Graphics and Visualization, APGV 7809, pages 125-125, New York, NY, USA. ACM.
- Casale, R., Alaa, L., Mallick, M., and Ring, H. (2009). Phantom limb related phenomena and their rehabilitation after lower limb amputation. Eur J Phys Rehabil Med, 45:559-566.
- Chertoff, D. B., Schatz, S. L., McDaniel, R., and Bowers, C. A. (2008). Improving presence theory through experiential design. Presence: Teleoper. Virtual Environ., 17:405-413.
- Cinder (2011). libcinder.org.
- Claypool, M. and Claypool, K. (2009). Perspectives, frame rates and resolutions: it's all in the game. In Proceedings of the 4th International Conference on Foundations of Digital Games, FDG 7809, pages 42-49, New York, NY, USA. ACM.
- Cole, J., Crowle, S., Austwick, G., and Slater, D. H. (2009). Exploratory findings with virtual reality for phantom limb pain; from stump motion to agency and analgesia. Disabil Rehabil, 31:846-854.
- Dahlquist, L. M., Herbert, L. J., Weiss, K. E., and Jimeno, M. (2010). Virtual-reality distraction and cold-pressor pain tolerance: does avatar point of view matter? Cyberpsychol Behav Soc Netw, 13:587-591.
- Desmond, D. M. and MacLachlan, M. (2006). Affective distress and amputation-related pain among older men with long-term, traumatic limb amputations. J Pain Symptom Manage, 31:362-368.
- Desmond, D. M., O'Neill, K., Paor, A. D., McDarby, G., and MacLachlan, M. (2006). Augmenting the reality of phantom limbs: Three case studies using an augmented mirror box procedure. Journal of Prosthetics and Orthotics, 18(3):74-79.
- Dolezal, J. M., Vernick, S. H., Khan, N., Lutz, D., and Tyndall, C. (1998). Factors associated with use and nonuse of an ak prosthesis in a rural, southern, geriatric population. Int J Rehabil Health, 4(4):245-251.
- Ehde, D. M., Czerniecki, J. M., Smith, D. G., Campbell, K. M., Edwards, W. T., Jensen, M. P., and Robinson, L. R. (2000). Chronic phantom sensations, phantom pain, residual limb pain, and other regional pain after lower limb amputation. Arch Phys Med Rehabil, 81:1039-1044.
- Eisemann, E., Assarsson, U., Schwarz, M., and Wimmer, M. (2009). Casting shadows in real time. In ACM SIGGRAPH ASIA 2009 Courses, SIGGRAPH ASIA 7809, New York, NY, USA. ACM.
- Ephraim, P. L., Wegener, S. T., MacKenzie, E. J., Dillingham, T. R., and Pezzin, L. E. (2005). Phantom pain, residual limb pain, and back pain in amputees: results of a national survey. Arch Phys Med Rehabil, 86:1910-1919.
- Ezendam, D., Bongers, R. M., and Jannink, M. J. (2009). Systematic review of the effectiveness of mirror therapy in upper extremity function. Disabil Rehabil, 31:2135-2149.
- FBX (2011). usa.autodesk.com.
- Flor, H. (2002). Phantom-limb pain: characteristics, causes, and treatment. Lancet Neurol, 1:182-189.
- Flor, H., Elbert, T., Knecht, S., Wienbruch, C., Pantev, C., Birbaumer, N., Larbig, W., and Taub, E. (1995). Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature, 375:482-484.
- Gibson, S., Cook, J., Howard, T., and Hubbold, R. J. (2002). ICARUS: Interactive reconstruction from uncalibrated images sequences. In SIGGRAPH 2002 Sketches and Applications Programme. San Antonio, Texas.
- Giraux, P. and Sirigu, A. (2003). Illusory movements of the paralyzed limb restore motor cortex activity. Neuroimage, 20 Suppl 1:S107-111.
- Giummarra, M. J., Georgiou-Karistianis, N., Nicholls, M. E., Gibson, S. J., Chou, M., and Bradshaw, J. L. (2011). The menacing phantom: What pulls the trigger? Eur J Pain, 15:1-8.
- Group, A. I. (2010). aig.cs.man.ac.uk.
- Gutierrez-Maldonado, J., Gutierrez-Martinez, O., Loreto, D., Penaloza, C., and Nieto, R. (2010). Presence, involvement and efficacy of a virtual reality intervention on pain. Stud Health Technol Inform, 154:97-101.
- Gutierrez-Martinez, O., Gutierrez-Maldonado, J., and Loreto-Quijada, D. (2011). Control over the virtual environment influences the presence and efficacy of a virtual reality intervention on pain. Stud Health Technol Inform, 167:111-115.
- Hänsel, A., Lenggenhager, B., von Känel, R., Curatolo, M., and Blanke, O. (2011). Seeing and identifying with a virtual body decreases pain perception. Eur J Pain.
- Hoffman, H. G., Seibel, E. J., Richards, T. L., Furness, T. A., Patterson, D. R., and Sharar, S. R. (2006). Virtual reality helmet display quality influences the magnitude of virtual reality analgesia. J Pain, 7:843-850.
- Hoffman, H. G., Sharar, S. R., Coda, B., Everett, J. J., Ciol, M., Richards, T., and Patterson, D. R. (2004). Manipulating presence influences the magnitude of virtual reality analgesia. Pain, 111:162-168.
- Hubbold, R., Cook, J., Keates, M., Gibson, S., Howard, T., Murta, A., West, A., and Pettifer, S. (2001). GNU/MAVERIK : A micro-kernel for large-scale virtual environments. Presence: Teloperators and Virtual Environments, 10:22-34. ISSN 1054-7460.
- Jensen, T. S. and Nikolajsen, L. (1994). Phantom limb pain and other phenomena after amputation. Churchill Livingstone.
- Kálmán, R. E. (1960). A new approach to linear filtering and prediction problems. Transactions of the ASMEJournal of Basic Engineering, 82(D):35-45.
- Katz, J. (1992). Psychophysiological contribution to phantom limbs. Can J Psychiatr, 37:282-282.
- Kooijman, C. M., Dijkstra, P. U., Geertzen, J. H., Elzinga, A., and van der Schans, C. P. (2000). Phantom pain and phantom sensations in upper limb amputees: an epidemiological study. Pain, 87:33-41.
- Krieg, J. C. (1993). Accuracy, resolution, latency and speed; key factors in virtual reality tracking environments. In Proceedings of the 3rd annual virtual reality conference and exhibition on VR becomes a business, pages 90-100, Westport, CT, USA. Meckler Corporation.
- Lamounier, E., Lopes, K., Cardoso, A., Andrade, A., and Soares, A. (2010). On the use of virtual and augmented reality for upper limb prostheses training and simulation. Conf Proc IEEE Eng Med Biol Soc, 2010:2451-2454.
- LaViola, Jr., J. J. and Litwiller, T. (2011). Evaluating the benefits of 3d stereo in modern video games. In Proceedings of the 2011 annual conference on Human factors in computing systems, CHI 7811, pages 2345- 2354, New York, NY, USA. ACM.
- Lee, J. C. (2008). Hacking the nintendo wii remote. IEEE Pervasive Computing, 7:39-45.
- Leyvand, T., Meekhof, C., Wei, Y.-C., Sun, J., and Guo, B. (2011). Kinect identity: Technology and experience. Computer, 44:94-96.
- Liebermann, D. I. (2010). Mirror Box Therapy. mirrorboxtherapy.com.
- Limbless Statistics (2011). www.limbless-statistics.org.
- Lindeman, R. W. and Beckhaus, S. (2009). Crafting memorable vr experiences using experiential fidelity. In Proceedings of the 16th ACM Symposium on Virtual Reality Software and Technology, VRST 7809, pages 187-190, New York, NY, USA. ACM.
- MacLachlan, M., McDonald, M., and Waloch, J. (2004). Mirror treatment of lower limb phantom pain: a case study. Disabil Rehabil, 26:901-904.
- Mahrer, N. E. and Gold, J. I. (2009). The use of virtual reality for pain control: a review. Curr Pain Headache Rep, 13:100-109.
- Malloy, K. M. and Milling, L. S. (2010). The effectiveness of virtual reality distraction for pain reduction: a systematic review. Clin Psychol Rev, 30:1011-1018.
- Manchikanti, L. and Singh, V. (2004). Managing phantom pain. Pain Physician, 7:365-375.
- McCabe, C. S., Haigh, R. C., Halligan, P. W., and Blake, D. R. (2005). Simulating sensorymotor incongruence in healthy volunteers: implications for a cortical model of pain. Rheumatology, 44(4):509-516.
- Mercier, C. and Sirigu, A. (2009). Training with virtual visual feedback to alleviate phantom limb pain. Neurorehabil Neural Repair, 23:587-594.
- Mitchell, S. W. (1872). Injuries of nerves and their consequences. J. B. Lippincott. Digitised at www.archive.org/details/injuriesofnerves00mitcuoft.
- Murray, C. D. (2005). The social meanings of prosthesis use. J Health Psychol, 3(10):425-441.
- Murray, C. D., Patchick, E., Caillette, F., Howard, T., and Pettifer, S. (2006a). Can immersive virtual reality reduce phantom limb pain? Medicine meets virtual reality: Accelerating change in healthcare, pages 407- 412.
- Murray, C. D., Patchick, E., Pettifer, S., and Howard, T. (2006b). Investigating the efficacy of a virtual mirror box in treating phantom limb pain in a sample of chronic sufferers. In Sharkey, P., Brooks, T., and Cobb, S., editors, Proceedings of The 6th International Conference on Disability, Virtual Reality and Associated Technologies, pages 167-174, Esbjerg, Denmark. ISBN 7 049 98 65 3.
- Murray, C. D., Patchick, E., Pettifer, S., Howard, T., Kalkarni, J., and Bamford, C. (2007a). Investigating the efficacy of a virtual mirror box in treating phantom limb pain in a sample of chronic sufferers. International Journal of Disability and Human Development, 5(3):227-234.
- Murray, C. D., Pettifer, S., Caillette, F., Patchick, E., and Howard, T. (2005). Immersive virtual reality as a rehabilitative technology for phantom limb experience. Proc IWVR 2005 4th Int Workshop Virtual Rehabi, pages 144-151.
- Murray, C. D., Pettifer, S., Caillette, F., Patchick, E., and Howard, T. (2006c). Immersive virtual reality as a rehabilitative technology for phantom limb experience: A protocol. CyberPsychol Behav, 2(9):167-170.
- Murray, C. D., Pettifer, S., Howard, T., E. Patchick, F. C., and Murray, J. (2010). Virtual solutions to phantom problems: Using immersive virtual reality to treat phantom limb pain. In Murray, C., editor, Amputation, Prosthesis and Phantom Limb Pain, pages 175-197. Springer. ISBN 0387874615.
- Murray, C. D., Pettifer, S., Howard, T., Patchick, E., Kalkarni, J., and Bamford, C. (2007b). The treatment of phantom limb pain using immersive virtual reality: three case studies. Disability and Rehabilitation, 29(18):1465-1469. ISSN 1464-5165 (electronic) 0963-8288 (paper).
- NASDAB (2002). National Amputation Statistical Database Annual Report. The Department of Health, Social Services and Public Safety (UK).
- Nintendo Wii (2011). www.nintendo.com/wii.
- NITE (2011). www.primesense.com.
- OpenNI (2011). www.openni.org.
- Pettifer, S. R., Thorne, D., McDermott, P., Marsh, J., Villéger, A., Kell, D. B., and Attwood, T. K. (2009). Visualising biological data: a semantic approach to tool and database integration. BMC Bioinformatics, 16.
- Radio 4, B. (2006). The Material World. www.bbc.co.uk/ radio4/science/thematerialworld 20061123.shtml.
- Ramachandran, V. S. and Rogers-Ramachandran, D. (1996). Synaesthesia in phantom limbs induced with mirrors. Proc Biol Sci, 341:377-386.
- Rutter, C. E., Dahlquist, L. M., and Weiss, K. E. (2009). Sustained efficacy of virtual reality distraction. J Pain, 10:391-397.
- Sato, K., Fukumori, S., Matsusaki, T., Maruo, T., Ishikawa, S., Nishie, H., Takata, K., Mizuhara, H., Mizobuchi, S., Nakatsuka, H., Matsumi, M., Gofuku, A., Yokoyama, M., and Morita, K. (2010). Nonimmersive virtual reality mirror visual feedback therapy and its application for the treatment of complex regional pain syndrome: an open-label pilot study. Pain Med, 11:622-629.
- Scherfgen, D. and Herpers, R. (2009). 3d tracking using multiple nintendo wii remotes: a simple consumer hardware tracking approach. In Proceedings of the 2009 Conference on Future Play on @ GDC Canada, Future Play 7809, pages 31-32, New York, NY, USA. ACM.
- Serafin, S. (2004). Sound design to enhance presence in photorealistic virtual reality. In Proceedings of the 10th Meeting of the International Conference on Auditory Display. International Community for Auditory Display.
- Sherman, R. A., Sherman, C. J., and Parker, L. (1984). Chronic phantom and stump pain among american veterans: results of a survey. Pain, 18:83-89.
- Sko, T. and Gardner, H. (2009). The wiimote with multiple sensor bars: creating an affordable, virtual reality controller. In Proceedings of the 10th International Conference NZ Chapter of the ACM's Special Interest Group on Human-Computer Interaction, CHINZ 7809, pages 41-44, New York, NY, USA. ACM.
- Slater, M. and Steed, A. (2000). A virtual presence counter. Presence: Teleoper. Virtual Environ., 9:413-434.
- Soler, M. D., Kumru, H., Pelayo, R., Vidal, J., Tormos, J. M., Fregni, F., Navarro, X., and Pascual-Leone, A. (2010). Effectiveness of transcranial direct current stimulation and visual illusion on neuropathic pain in spinal cord injury. Brain, 133:2565-2577.
- Sparkfun (2011). www.sparkfun.com.
- Vuzix (2011). www.vuzix.com/consumer/products vr920.h tml.
- Welch, G. F. (2009). History: The use of the kalman filter for human motion tracking in virtual reality. Presence: Teleoper. Virtual Environ., 18:72-91.
- Wender, R., Hoffman, H. G., Hunner, H. H., Seibel, E. J., Patterson, D. R., and Sharar, S. R. (2009). Interactivity influences the magnitude of virtual reality analgesia. J Cyber Ther Rehabil, 2:27-33.
- Williamson, G. M., Schulz, R., Bridges, M. W., and Behan, A. M. (1994). Social and psychological factors in adjustment to limb amputation. J Soc Behav Personal, 3(10):425-441.
- Witmer, B. G. and Singer, M. J. (1998). Measuring presence in virtual environments: A presence questionnaire. Presence: Teleoper. Virtual Environ., 7:225- 240.
- XBee (2011). www.digi.com/xbee.
- Xbox 360 Kinect (2011). www.xbox.com/kinect.
- Zeigler-Graham, K., MacKenzie, E. J., L.Ephraim, P., Travison, T. G., and Brookmeyer, R. (2008). Estimating the prevalence of limb loss in the United States - 2005 to 2050. Archives of Physical Medicine and Rehabilitation, 89:422-429.
Paper Citation
in Harvard Style
Pettifer S., Howard T., Blundell B., Edwards D. and Lieberman I. (2012). AN IMMERSIVE VIRTUAL ENVIRONMENT FOR PHANTOM LIMB PAIN REHABILITATION . In Proceedings of the International Conference on Computer Graphics Theory and Applications and International Conference on Information Visualization Theory and Applications - Volume 1: GRAPP, (VISIGRAPP 2012) ISBN 978-989-8565-02-0, pages 426-433. DOI: 10.5220/0003831704260433
in Bibtex Style
@conference{grapp12,
author={Steve Pettifer and Toby Howard and Ben Blundell and David Edwards and Ilan Lieberman},
title={AN IMMERSIVE VIRTUAL ENVIRONMENT FOR PHANTOM LIMB PAIN REHABILITATION},
booktitle={Proceedings of the International Conference on Computer Graphics Theory and Applications and International Conference on Information Visualization Theory and Applications - Volume 1: GRAPP, (VISIGRAPP 2012)},
year={2012},
pages={426-433},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003831704260433},
isbn={978-989-8565-02-0},
}
in EndNote Style
TY - CONF
JO - Proceedings of the International Conference on Computer Graphics Theory and Applications and International Conference on Information Visualization Theory and Applications - Volume 1: GRAPP, (VISIGRAPP 2012)
TI - AN IMMERSIVE VIRTUAL ENVIRONMENT FOR PHANTOM LIMB PAIN REHABILITATION
SN - 978-989-8565-02-0
AU - Pettifer S.
AU - Howard T.
AU - Blundell B.
AU - Edwards D.
AU - Lieberman I.
PY - 2012
SP - 426
EP - 433
DO - 10.5220/0003831704260433