4D distance map would involve a significant com-
putational cost. Variational interpolation (Turk and
O’Brien, 1999) is also very difficult to extend to gray-
scale volumes. Using the extension scheme of Udupa
and Grevera (Grevera and Udupa, 1996), the gray-
scale volumes could be treated as height fields defined
over the 3D space. Since these height fields can be
represented by 4D IFs, the shape transformation be-
tween them would require a 4D RBF interpolation. To
avoid the loss of fine details, at least to each voxel a
4D RBF needs to be assigned. Thus, for a pair of vol-
umes with resolution 256
3
, the number of unknown
variables is 256
3
× 2. Consequently, the coefficient
matrix of the corresponding linear equation system
contains 256
6
× 4 elements, which makes the inver-
sion practically impossible. Overall, we think that
compared to the computational and storage costs of
the previous methods, our soution is simple and effi-
cient.
5 CONCLUSION
In this paper, we have introduced a novel algorithm
for shape-based interpolation of gray-scale images
and volumes. As far as we know, our technique is
the first to combine distribution interpolation and the
Radon transform. The major advantage of this com-
bination is that the Radon transform does not require
a one dimension higher representation than the orig-
inal images and volumes. This is not the case for
the previous IF methods, where the gray-scale images
and volumes can alternatively be represented by 3D
and 4D IFs, respectively. Moreover, we demonstrated
that the distribution interpolation of the Radon trans-
forms can make a smooth connection between non-
overlapping features that the IF methods are typically
not able to connect. Due to this advantageous proper-
ties, we think that our method represents a significant
contribution to the field of shape-based interpolation.
ACKNOWLEDGEMENTS
This work was supported by projects T
´
AMOP-
4.2.2.B-10/1–2010-0009 and OTKA K-101527. The
Heloderma data set is from the Digital Morphology
(http://www.digimorph.org) data archive. Special
thanks to Dr. Jessica A. Maisano for making this data
set available to us.
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