Laser Speckle Contrast Images - Processing of Data to Analyze Microvascular Variations in Hand Skin of Healthy Subjects
Anne Humeau-Heurtier, Jérémy Dexet, Pierre Abraham, Guillaume Mahé
2014
Abstract
Diseases such as frostbite, Raynaud’s phenomenon, carpal tunnel syndrome, systemic sclerosis, hand burns, hand flaps or hand wounds lead to microvascular dysfunctions. These diseases can affect only one hand and even sometimes only some fingers. Therefore, in order to quantify the microvascular alterations, it can be useful to compare microvascular perfusion of both hands (altered versus healthy hand). However, skin microvasculature presents spatial variations and the possibility to directly compare perfusion values of the two hands has not been studied yet. We therefore propose to quantify these spatial variations. For this purpose, perfusion values from laser speckle contrast images (LSCI) of the two hands (dorsal faces) from seven young healthy subjects are acquired simultaneously and then processed. The results show that the dorsal faces of the two hands in our young healthy subjects present close perfusion values (average coefficient of variation less than 9% for our subjects). These findings are preliminary observations to quantify the microvascular alterations in the above-mentioned diseases. The coefficient of variation in diseased states remains to be studied in order to see whether LSCI could be of interest to improve the diagnosis of hand skin pathologies.
References
- Barachini, P., Vezzoni, G. M., Palombo, C., Franzoni, F., and Bigalli, G. (2004). Skin blood flow pattern in burns outcomes. Burns, 30:312-316.
- Briers, J. D. and Webster, S. (1996). Laser speckle contrast analysis (lasca): a non- scanning, full-field technique for monitoring capillary blood flow. J. Biomed. Opt., 1:174-179.
- Brown, S. (2012). Diagnosis and management of patients with raynaud's phenomenon. Nurs. Stand., 26:41-46.
- DeAngelis, R., Grassi, W., and M.Cutolo (2009). A growing need for capillaroscopy in rheumatology. Arthritis Rheum., 61:405-410.
- Draijer, M., Hondebrink, E., van Leeuwen, T., and Steenbergen, W. (2009). Review of laser speckle contrast techniques for visualizing tissue perfusion. Lasers Med. Sci., 24:639-651.
- Du, Z., Zan, T., Li, H., and Li, Q. (2011). A study of blood flow dynamics in flap delay using the full-field laser perfusion imager. Microvasc. Res., 82:284-290.
- Fercher, A. F. and Briers, J. D. (1981). Flow visualization by means of single-exposure speckle photography. Opt. Commun., 37:326-330.
- Foray, J. (1992). Mountain frostbite. current trends in prognosis and treatment (from results concerning 1261 cases). Int. J. Sports Med., 13:S193-S196.
- Gladue, H., Maranian, P., Paulus, H. E., and Khanna, D. (2013). Evaluation of test characteristics for outcome measures used in raynaud's phenomenon clinical trials. Arthritis Care Res (Hoboken), 65:630-636.
- Herrick, A. L. (2000). Vascular function in systemic sclerosis. Curr. Opin. Rheumatol., 12:527-533.
- Hopkins, W. G. (2000). Measures of reliability in sports medicine and science. Sports Medicine, 30:1-15.
- Humeau-Heurtier, A., Guerreschi, E., Abraham, P., and Mahe, G. (2013a). Relevance of laser doppler and laser speckle techniques for assessing vascular function: state of the art and future trends. IEEE Trans. Biomed. Eng., 60:659-666.
- Humeau-Heurtier, A., Mahe, G., Durand, S., and Abraham, P. (2013b). Multiscale entropy study of medical laser speckle contrast images. IEEE Trans. Biomed. Eng., 60:872-879.
- Mahe, G., Durand, S., Humeau, A., Leftheriotis, G., Rousseau, P., and Abraham, P. (2012a). Air movements interfere with laser speckle contrast imaging recordings. Lasers Med. Sci., 27:1073-1076.
- Mahe, G., Haj-Yassin, F., Rousseau, P., Humeau, A., Durand, S., Leftheriotis, G., and Abraham, P. (2011). Distance between laser head and skin does not influence skin blood flow values recorded by laser speckle imaging. Microvasc. Res., 82:439-442.
- Mahe, G., Humeau-Heurtier, A., Durand, S., Leftheriotis, G., and Abraham, P. (2012b). Assessment of skin microvascular function and dysfunction with laser speckle contrast imaging. Circulation: Cardiovasc. Imaging, 5:155-163.
- Mahe, G., Humeau-Heurtier, A., Durand, S., Leftheriotis, G., and Abraham, P. (2012c). Impact of experimental conditions on non-contact laser recordings in microvascular studies. Microcirc., 19:669-675.
- Meier, T. O., Guggenheim, M., Vetter, S. T., Husmann, M., Haile, S. R., and Amann-Vesti, B. R. (2011). Microvascular regeneration in meshed skin transplants after severe burns. Burns, 37:1010-1014.
- Miao, P., Rege, A., Li, N., Thakor, N. V., and Tong, S. (2010). High resolution cerebral blood flow imaging by registered laser speckle contrast analysis. IEEE Trans. Biomed. Eng., 57:1152-1157.
- Rege, A., Senarathna, J., Li, N., and Thakor, N. V. (2012). Anisotropic processing of laser speckle images improves spatiotemporal resolution. IEEE Trans. Biomed. Eng., 59:1272-1280.
- Shannon, H. and Rizzolo, D. (2012). Carpal tunnel syndrome: symptoms, diagnosis, and treatment options. JAAPA, 25:22-26.
- Soderstrom, T., Svensson, H., Koop, T., and Moller, K. O. (1999). Processing of laser-doppler signals from free flaps. Technol. Health Care, 7:219-223.
- Wigley, F. M. (2009). Vascular disease in scleroderma. Clin. Rev. Allergy Immunol., 36:150-175.
Paper Citation
in Harvard Style
Humeau-Heurtier A., Dexet J., Abraham P. and Mahé G. (2014). Laser Speckle Contrast Images - Processing of Data to Analyze Microvascular Variations in Hand Skin of Healthy Subjects . In Proceedings of the International Conference on Bioimaging - Volume 1: BIOIMAGING, (BIOSTEC 2014) ISBN 978-989-758-014-7, pages 55-58. DOI: 10.5220/0004892900550058
in Bibtex Style
@conference{bioimaging14,
author={Anne Humeau-Heurtier and Jérémy Dexet and Pierre Abraham and Guillaume Mahé},
title={Laser Speckle Contrast Images - Processing of Data to Analyze Microvascular Variations in Hand Skin of Healthy
Subjects},
booktitle={Proceedings of the International Conference on Bioimaging - Volume 1: BIOIMAGING, (BIOSTEC 2014)},
year={2014},
pages={55-58},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004892900550058},
isbn={978-989-758-014-7},
}
in EndNote Style
TY - CONF
JO - Proceedings of the International Conference on Bioimaging - Volume 1: BIOIMAGING, (BIOSTEC 2014)
TI - Laser Speckle Contrast Images - Processing of Data to Analyze Microvascular Variations in Hand Skin of Healthy
Subjects
SN - 978-989-758-014-7
AU - Humeau-Heurtier A.
AU - Dexet J.
AU - Abraham P.
AU - Mahé G.
PY - 2014
SP - 55
EP - 58
DO - 10.5220/0004892900550058