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4 CONCLUSIONS
We developed CG-TM for university students,
concerning reactions involving a drastic change in
the structures of the reactants in the following
chlorination reactions: S
N
1, formation of tert-butyl
chloride from tert-butanol; S
N
2, formation of 1-
chlorobutane from 1-butanol. The CG-TM could
clearly demonstrate the changes in the structures
during the reaction by the ball-and-stick model, in
addition to the image of the energy change by the
reaction profile. An electronic lab-book for chemical
experiments in the students’ laboratory at the
university was produced. The lab-book could display
pictures of the apparatus, flow chart of the
experimental procedure, and reaction mechanism
with the CG-TM. A preliminary study on the
effectiveness of the CG-TM suggested that students
were able to obtain the image of the S
N
1 and S
N
2
reactions.
ACKNOWLEDGEMENTS
This work was supported by JSPS KAKENHI Grant
Numbers 25350188, 26350227.
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