Expression of VEGF on Mucosal Cavity’s Chronic Inflammation after the Provision of Clarias Batrachus Fish Oil

Theresia Indah Budhy, Istiati, Ni Made Titia Prabandari Iswara

2017

Abstract

Chronic inflammation is caused by an agent that becomes settled during a long-term period. If the inflammation is not solved it will make the tissue damage wider. VEGF is a growth factor that is necessary during the healing period of chronic inflammation as signaling proteins in the process of angiogenesis. Fish oil Clarias batrachus is known to have a role as antioxidant that can accelerate the healing of chronic inflammation. The aim of this study was to determine the expression of VEGF after the provision of catfish’s fish oil, Clarias batrachus. The study was conducted on 19 mice (Rattus novergicus) in regard to chronic mucosal inflammation by the application 10% hydrogen peroxide and then they were given fish oil extracts on the third day with 5% fish oil extract given to treatment group 1 and 10% fish oil extract given to treatment group 2. Samples were decapitated on the third day after treatment and then made into preparations with IHC staining. Then the expression of VEGF was counted quantitatively. The amount of expression of VEGF in the treatment group given fish oil extracts of catfish had higher averages of 50.28 at 10% concentration and 32.71 at 5% concentration compared to the control group which was 13.60. Fish oil extracts of catfish (Clarias batrachus) can increase the expression of VEGF in chronic inflammation at a 10% level of concentration.

Paper Citation

in Harvard Style

Budhy T., Istiati. and Iswara N. (2017). Expression of VEGF on Mucosal Cavity’s Chronic Inflammation after the Provision of Clarias Batrachus Fish Oil.In Proceedings of the 7th International Meeting and the 4th Joint Scientific Meeting in Dentistry - Volume 1: TIMNAS7-JSMID4, ISBN 978-989-758-341-4, pages 200-203. DOI: 10.5220/0007294902000203

in Bibtex Style

@conference{timnas7-jsmid417,
author={Theresia Indah Budhy and Istiati and Ni Made Titia Prabandari Iswara},
title={Expression of VEGF on Mucosal Cavity’s Chronic Inflammation after the Provision of Clarias Batrachus Fish Oil},
booktitle={Proceedings of the 7th International Meeting and the 4th Joint Scientific Meeting in Dentistry - Volume 1: TIMNAS7-JSMID4,},
year={2017},
pages={200-203},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007294902000203},
isbn={978-989-758-341-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 7th International Meeting and the 4th Joint Scientific Meeting in Dentistry - Volume 1: TIMNAS7-JSMID4,
TI - Expression of VEGF on Mucosal Cavity’s Chronic Inflammation after the Provision of Clarias Batrachus Fish Oil
SN - 978-989-758-341-4
AU - Budhy T.
AU - Istiati.
AU - Iswara N.
PY - 2017
SP - 200
EP - 203
DO - 10.5220/0007294902000203