High-Calorie Diet Reduces Neuroglia Count

Nilam Anggraeni, Kristanti Wanito Wigati, I Lukitra Wardani, Lilik Herawati

2017

Abstract

Abstract: Nowadays, high-calorie food consumption people can unwittingly affect health. Several studies have reported the effects of excesshigh-calorie food consumption can range fromhyperglycaemia to neurodegenerative interference. In the brain, astrocytes function to respond to the changing modificationof molecular brain environment.structure. This study aimed to observe the effect of a high-calorie diet on the brain histology of male mice (Mus musculus). In this study, 28 mice were randomly divided into 4 groups: the control group pre (K0); the control group post with a standard diet (K1) ;the treatment group with 0.15g of glucose diet (K2); and the treatment group with 0.25g of glucose diet (K3). Treatment was given everyday for eightweeks. Brains were then histologically processed and stained with Haematoxylin-Eosin (HE) and observation made of quantitative changes of astrocytes in the cerebral cortex. Results: Data were analyzed with Post-Hoc ANOVA. From the study, significant differences were found between K0 and K2 (α <0.05). In addition, significant differences were obtained in the groups K0 and K3 (α <0.05). Meanwhile, no significant differences were found between groups (α> 0.05). In conclusion, a high-calorie diet affects thee brain histology of male mice.

Paper Citation

in Harvard Style

Anggraeni N., Wanito Wigati K., Lukitra Wardani I. and Herawati L. (2017). High-Calorie Diet Reduces Neuroglia Count.In Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS, ISBN 978-989-758-340-7, pages 169-173. DOI: 10.5220/0007335001690173

in Bibtex Style

@conference{sips17,
author={Nilam Anggraeni and Kristanti Wanito Wigati and I Lukitra Wardani and Lilik Herawati},
title={High-Calorie Diet Reduces Neuroglia Count},
booktitle={Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,},
year={2017},
pages={169-173},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007335001690173},
isbn={978-989-758-340-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,
TI - High-Calorie Diet Reduces Neuroglia Count
SN - 978-989-758-340-7
AU - Anggraeni N.
AU - Wanito Wigati K.
AU - Lukitra Wardani I.
AU - Herawati L.
PY - 2017
SP - 169
EP - 173
DO - 10.5220/0007335001690173