The Correlation of Norovirus Infection to Severity Degree of Acute Diarrhea in Children Under Five Years Old in Mataram City, Lombok

Warda Elmaida, Juniastuti, Soetjipto

2017

Abstract

Abstract: Background: Norovirus has been recognized as a leading cause of acute diarrhea in all age groups, especially infants and children under five years old. Acute diarrhea is still a problem in Mataram City, Lombok, Nusa Tenggara Barat (NTB), and there has been no research into the causes of acute diarrhea there. Objective: This study aimed to investigate the possible correlation between norovirus infection and the severity degree of acute diarrhea in children under five years old in Mataram City, Lombok, NTB. Methods: Stool samples (n = 38) were collected from children aged <5 years with diagnoses of acute diarrhea at Mataram General Hospital during the period May–July 2017. The stool samples were tested for norovirus antigens using reverse transcription polymerase chain reaction (RT-PCR) at the Tropical Disease Center laboratory. The severity degree of acute diarrhea was assessed using a Vesikari score and then the norovirus infections were compared in terms of severity degree of acute diarrhea. Results: Twelve (31.5%) of the stool samples were positive for norovirus infection. Severe diarrhea (Vesikari score ≥11) was reported in ten (27%) children, moderate diarrhea (Vesikari score 7–10) was reported in six (16%) children, and mild diarrhea (Vesikari score <7) was reported in 22 (54%) children. Among those with norovirus infections, moderate diarrhea was reported in two (16%) children and severe diarrhea was reported in ten (84%) children. Conclusion: The results of this study indicate some association between norovirus infection and severity degree of acute diarrhea. There was a significant result regarding the relationship between the level of acute diarrhea and norovirus infection as examined by a Vesikari score.

Paper Citation

in Harvard Style

Elmaida W., Juniastuti. and Soetjipto. (2017). The Correlation of Norovirus Infection to Severity Degree of Acute Diarrhea in Children Under Five Years Old in Mataram City, Lombok.In Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS, ISBN 978-989-758-340-7, pages 316-320. DOI: 10.5220/0007338403160320

in Bibtex Style

@conference{sips17,
author={Warda Elmaida and Juniastuti and Soetjipto},
title={The Correlation of Norovirus Infection to Severity Degree of Acute Diarrhea in Children Under Five Years Old in Mataram City, Lombok},
booktitle={Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,},
year={2017},
pages={316-320},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007338403160320},
isbn={978-989-758-340-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,
TI - The Correlation of Norovirus Infection to Severity Degree of Acute Diarrhea in Children Under Five Years Old in Mataram City, Lombok
SN - 978-989-758-340-7
AU - Elmaida W.
AU - Juniastuti.
AU - Soetjipto.
PY - 2017
SP - 316
EP - 320
DO - 10.5220/0007338403160320