Histopathologic Feature of Breast Cancer Patients in Young Women

M. S. Sitorus, L. I. Laksmi

2018

Abstract

Breast malignancy is still the most common cancer in the worldwide that attacks women. Causing a high mortality rate that is about 15% of all deaths in women. The incidence of breast cancer cases in young age under the 40 years of age is low but they have particular attention because of its unique behavior. Breast cancer biology in young women is more aggressive than women of premenopausal age. This is related to many factors associated with poor prognosis, including high proliferation index, grade three and four disease and negative Estrogen Receptor expression. This study aims to explore further histopathologic feature, immunohistochemical expression, and subtype of breast cancer biology, in women under 40 years of age. It was found that the most common type, of breast cancer histopathology was invasive breast cancer (88%). The most histopathologic grading was grade I which is 74%. Based on the ER immunohistochemical staining found that 60% gives a negative expression, only 40% gives positive. A total of 68% gave a positive PR expression, 68% Her-2 positive one, 30% Her-2 positive three. As many as 56% positive Ki-67. All cases are Her-2 positive and have a moderate to poor prognosis.

Paper Citation

in Harvard Style

Sitorus M. and Laksmi L. (2018). Histopathologic Feature of Breast Cancer Patients in Young Women.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 578-581. DOI: 10.5220/0010079205780581

in Bibtex Style

@conference{icosteerr18,
author={M. S. Sitorus and L. I. Laksmi},
title={Histopathologic Feature of Breast Cancer Patients in Young Women},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={578-581},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010079205780581},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - Histopathologic Feature of Breast Cancer Patients in Young Women
SN - 978-989-758-449-7
AU - Sitorus M.
AU - Laksmi L.
PY - 2018
SP - 578
EP - 581
DO - 10.5220/0010079205780581