The Correlation of Fasting and 2-Hours Postprandial Plasma Glucose with Glycated Hemoglobin as Glycemic Control

Mutiara Indah Sari, Milahayati Daulay, Dian Dwi Wahyuni, Zaimah Z. Tala

2018

Abstract

Diabetes Mellitus (DM) is one of the non-communicable diseases that are currently increasing in number. One of the indicators that used to describe the longer period of glycemic control in patients with DM is the level of glycated hemoglobin or HbA1c. The purpose of this study was to determine whether in fasting or 2- hours postprandial plasma glucose (PPG) level correlated with HbA1c level. So it can be used as the glycemic control when measurement of the HbA1c is not available. This study is a cross-sectional study, on 60 type 2 diabetes mellitus patients at the University of Sumatera Utara Hospital. Before the examination, respondents are required to fast for 10-12 hours. Examination of fasting plasma glucose (FPG) and 2-hours PPG were performed using a cobas 6000 analyzer with hexokinase and immunoturbidimetry method. HbA1c was measured using high-performance liquid chromatography (HPLC) method. The correlation between FPG with HbA1c and 2-hours PPG with HbA1c was analyzed with the Spearman bivariate correlation test by SPSS 22 version. We found that the mean and SD values of FPG, 2-hours PPG, and HbA1c were 186.31 ± 71.27, 284.88 ± 92.06 and 8.85 ± 1.73, respectively. The Spearman bivariate correlation indicated a significant association (p = 0.005, r = 0.357) between FPG with HbA1c. In this study found that no correlation between 2-hours PPG with HbA1c (p = 0.780, r = 0.036). We conclusions, FPG indicated as glycemic control better than 2-hours PPG on type 2 diabetic if the HbA1c examination is not available.

Paper Citation

in Harvard Style

Sari M., Daulay M., Wahyuni D. and Tala Z. (2018). The Correlation of Fasting and 2-Hours Postprandial Plasma Glucose with Glycated Hemoglobin as Glycemic Control.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 605-609. DOI: 10.5220/0010080206050609

in Bibtex Style

@conference{icosteerr18,
author={Mutiara Indah Sari and Milahayati Daulay and Dian Dwi Wahyuni and Zaimah Z. Tala},
title={The Correlation of Fasting and 2-Hours Postprandial Plasma Glucose with Glycated Hemoglobin as Glycemic Control},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={605-609},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010080206050609},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - The Correlation of Fasting and 2-Hours Postprandial Plasma Glucose with Glycated Hemoglobin as Glycemic Control
SN - 978-989-758-449-7
AU - Sari M.
AU - Daulay M.
AU - Wahyuni D.
AU - Tala Z.
PY - 2018
SP - 605
EP - 609
DO - 10.5220/0010080206050609