Correlation of Glycated Hemoglobin and D-dimer in Diabetic Patient

Sry Suryani Widjaja, Muhammad Syahputra

2018

Abstract

Diabetes Mellitus a chronic metabolic disease presented with chronic hyperglycemia, which will cause abnormalities in the endothelial cells, proinflammatory state, alter platelet function and plasma coagulation factors that lead to hypercoagulable state and thrombosis. D-dimer an indirect marker of thrombotic activity, is the final fragment of the plasmin mediated degradation of cross-linked fibrin. The elevated d-dimer level was detected at the onset of thrombosis, it was used to exclude the venous thromboembolism when it was negative. D-dimer was increased in diabetic patients under most studies, and when there is a hypercoagulable state, hyperfibrinolysis will occur, subsequently elevation of D-dimer. This study was aimed to study the correlation between glycated hemoglobin and d-dimer in diabetic patients. This is a case control study to evaluate the correlation of glycated hemoglobin (HbA1c) and d-dimer in diabetic patients. Total 60 patients were recruited, the blood glucose level, HbA1c, d-dimer were measured. There was statatistical significant correlation between HbA1C and d-dimer (p=0.019, r= 0.27), HbA1c and age (p=0.002, r=0.36), d-dimer and age (p=0.04), blood glucose and HbA1C (p=0.00, r=0.5), blood glucose and age (p=0.037, r=0.23).

Paper Citation

in Harvard Style

Widjaja S. and Syahputra M. (2018). Correlation of Glycated Hemoglobin and D-dimer in Diabetic Patient.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 648-651. DOI: 10.5220/0010082206480651

in Bibtex Style

@conference{icosteerr18,
author={Sry Suryani Widjaja and Muhammad Syahputra},
title={Correlation of Glycated Hemoglobin and D-dimer in Diabetic Patient},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={648-651},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010082206480651},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - Correlation of Glycated Hemoglobin and D-dimer in Diabetic Patient
SN - 978-989-758-449-7
AU - Widjaja S.
AU - Syahputra M.
PY - 2018
SP - 648
EP - 651
DO - 10.5220/0010082206480651