Profile of Clinical Chemistry and Hematology of Long-tailed Macaques (Macacafascicularis) During Adaptation after Administration of Methanol Extract of Bitter Melon Seed (Momordicacharantia) and DMPA

Syafruddin Ilyas, Masitta Tanjung, Deri Edianto

2018

Abstract

For the use of non-human primate animals (Macacafascicularis) as an advanced test of a drug substance, it is necessary to measure the clinical chemistry content [blood sugar levels, SGOT (Serum Glutamic Oxaloacetic Transaminase)/ SGP (Serum Glutamate Pyruvate Transaminase), and creatinine] and hematology, especially white blood cells such as; Neutrophils, Lymphocytes, Monocytes, Eusinophils and Basophils. Giving of bitter melon seed extract for six days and injection of DMPA (Depot medroxyprogesterone acetate) at the beginning of the study gives a profile of daily blood sugar level, SGOT/SGPT, creatinine, and Neutrophil, Lymphocyte, Monocyte, Eusinophil and Basophil did not show any significant difference (p>0.05). It was concluded that pare seed extract can be continued in the next experiment to increase the day of extracting methanol extract of pare seed and DMPA on long-tailed macaque.

Paper Citation

in Harvard Style

Ilyas S., Tanjung M. and Edianto D. (2018). Profile of Clinical Chemistry and Hematology of Long-tailed Macaques (Macacafascicularis) During Adaptation after Administration of Methanol Extract of Bitter Melon Seed (Momordicacharantia) and DMPA.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 799-803. DOI: 10.5220/0010091307990803

in Bibtex Style

@conference{icosteerr18,
author={Syafruddin Ilyas and Masitta Tanjung and Deri Edianto},
title={Profile of Clinical Chemistry and Hematology of Long-tailed Macaques (Macacafascicularis) During Adaptation after Administration of Methanol Extract of Bitter Melon Seed (Momordicacharantia) and DMPA},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={799-803},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010091307990803},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - Profile of Clinical Chemistry and Hematology of Long-tailed Macaques (Macacafascicularis) During Adaptation after Administration of Methanol Extract of Bitter Melon Seed (Momordicacharantia) and DMPA
SN - 978-989-758-449-7
AU - Ilyas S.
AU - Tanjung M.
AU - Edianto D.
PY - 2018
SP - 799
EP - 803
DO - 10.5220/0010091307990803