Immunohistochemistry Expression of Ki-67 in Nodular Hyperplasia, Prostatic Intraepithelial Neoplasia and Adenocarcinoma Prostate

Lidya Imelda Laksmi, T. Ibnu Alferraly

2018

Abstract

Immunohistochemistry Ki67 is a marker of cell proliferation. This descriptive study was performed in the Department of Anatomical Pathology Universitas Sumatera Utara, Medan, Indonesia. A total of 86 paraffin blocks prepared from transurethral resection of the prostate (TUR-P) were collected in this study. The specimens divided as three lesions; nodular hyperplasia, prostatic intraepithelial neoplasia (PIN) and adenocarcinoma prostate. In this study a total of 86 specimens from TUR-P, we divided them using IHK p63 as three lesions; (1). Nodular hyperplasia prostate, frequency 31 (36%), (2). Prostatic intraepithelial neoplasia 17 (19,8%), and (3). Adenocarcinoma prostate 38 (44,2%). Our results show the expression Ki67 in nodular hyperplasia is (9.65 ± 11.577), median: 5; Prostatic intraepithelial neoplasia (14.71 ± 14.67), median 7 and adenocarcinoma prostate (57.53 ± 27.57), median 50. This study concluded that in prostate tissue examination, immunohistochemistry expression of Ki67 are different in nodular hyperplasia, PIN and prostate adenocarcinoma. Whereas the expression of Ki67 is higher in adenocarcinoma than PIN and nodular hyperplasia.

Paper Citation

in Harvard Style

Laksmi L. and Alferraly T. (2018). Immunohistochemistry Expression of Ki-67 in Nodular Hyperplasia, Prostatic Intraepithelial Neoplasia and Adenocarcinoma Prostate.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 884-886. DOI: 10.5220/0010098308840886

in Bibtex Style

@conference{icosteerr18,
author={Lidya Imelda Laksmi and T. Ibnu Alferraly},
title={Immunohistochemistry Expression of Ki-67 in Nodular Hyperplasia, Prostatic Intraepithelial Neoplasia and Adenocarcinoma Prostate},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={884-886},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010098308840886},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - Immunohistochemistry Expression of Ki-67 in Nodular Hyperplasia, Prostatic Intraepithelial Neoplasia and Adenocarcinoma Prostate
SN - 978-989-758-449-7
AU - Laksmi L.
AU - Alferraly T.
PY - 2018
SP - 884
EP - 886
DO - 10.5220/0010098308840886