Platelet Profile Distribution in Critically Ill Children

Gema Nazri Yanni, Rina Amalia C. Saragih

2018

Abstract

Thrombocytopenia occurring in a critically ill patient is the result of hemodilution, increased platelet consumption, an immune mechanism (increased platelet destruction), and increased platelet sequestration. Previous studies showed that platelet indices might be a more useful prognostic indicator, but a study on critically ill children is still limited. We report the platelet profile of critically ill children admitted in the pediatric intensive care unit. This report is part of an ongoing study of the prognostic marker in critically ill children that consist of septic and non-septic patients. All patients admitted to the pediatric intensive care unit Haji Adam Malik Hospital and Universitas Sumatera Utara Hospital were recruited. We examined the platelet profile (platelet count, Plateletcrit/PCT, Mean Platelet Volume /MPV and Platelet Distribution Width/PDW) on the first day of admission. Of 53 samples, 29 were boys with an average age of 7.62 (+6.43) years old. Severe malnutrition was found in 12 cases (22.6%). We found platelet count median value was 316000 (23000-828000). Median value of PCT, MPV, and PDW were 0.32 (0.08-1.40), 9.4 (7.9- 13.5), 9.7 (7.0-17.5), respectively. As the conclusion of this ongoing study, it is shown that there were changes of platelet profile in critically ill children. Further studies studying its usefulness as a prognostic indicator are still needed.

Paper Citation

in Harvard Style

Yanni G. and Saragih R. (2018). Platelet Profile Distribution in Critically Ill Children.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 887-890. DOI: 10.5220/0010098808870890

in Bibtex Style

@conference{icosteerr18,
author={Gema Nazri Yanni and Rina Amalia C. Saragih},
title={Platelet Profile Distribution in Critically Ill Children},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={887-890},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010098808870890},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - Platelet Profile Distribution in Critically Ill Children
SN - 978-989-758-449-7
AU - Yanni G.
AU - Saragih R.
PY - 2018
SP - 887
EP - 890
DO - 10.5220/0010098808870890