Ocular Abnormalities in Correlation with Multi-transfused in Children with Beta Thalassemia Major

B. Lubis, S. M. Lubis

2018

Abstract

Thalassemia is the commonest haemoglobinopathies worldwide. Repeated blood transfusion lead to hemosiderosis which affects all the organ in the body including eyes. The aim of this study was to evaluate ocular abnormalities in children with beta thalassemia major who have received multiple blood transfusions. A cross-sectional study was conducted in the Thalassemia day-care centre of a tertiary care at H. Adam Malik Hospital Medan, Indonesia. Visual aquity, anterior segment, fundus, and retina were evaluated to screen ocular abnormalities. There were 37 patients with beta thalassemia major, male and female were 20 (51.3%) and 17 (48.7%), respectively, age 3 to 18 years. All patients received regular blood transfusions, but only 28 patients (78.4%) received iron chelation therapy. Opthalmologic examinations showed ocular abnormalities in 15 subjects (40.4%), cataract in 3 patients (8.1%), papil edema in 10 patients (27%), and papil atrophy in 2 patients (5.4%). Decreased visual acuity was observed in 8 patient (21.6%). Hyperpigmentation in bulbar conjunctiva were seen in 12 patients (32.4%). There was no significant correlation between ocular abnormalities and multiple transfusions. Regular ophthalmologic evaluations was needed to detect retinopathy and early changes in their ocular system for a better quality of life in thalassemic patients.

Paper Citation

in Harvard Style

Lubis B. and Lubis S. (2018). Ocular Abnormalities in Correlation with Multi-transfused in Children with Beta Thalassemia Major.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 898-903. DOI: 10.5220/0010099508980903

in Bibtex Style

@conference{icosteerr18,
author={B. Lubis and S. M. Lubis},
title={Ocular Abnormalities in Correlation with Multi-transfused in Children with Beta Thalassemia Major},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={898-903},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010099508980903},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - Ocular Abnormalities in Correlation with Multi-transfused in Children with Beta Thalassemia Major
SN - 978-989-758-449-7
AU - Lubis B.
AU - Lubis S.
PY - 2018
SP - 898
EP - 903
DO - 10.5220/0010099508980903