Antibacterial-based Hand Sanitizer of Biwa Leaves’ Extract (Eriobotrya japonica (Thunb) Lindl) from Tanah Karo

Irfan Asahan, Slamet Silaban, Arif M. Harahap, Dwi Suryanto

2018

Abstract

Biwa (Eriobotrya japonica (Thunb) Lindl.) is one of cultivated plant commodities in Karo regency, North Sumatera, which has been known to contain chemical compounds such as flavonoid and tannin possessing antibacteria properties. The study aimed to develop the potency of Biwa leaves’ extract as hand sanitizer to inhibit the growth of Staphylococcus aureus. Methodologies in this study were extraction and detection of common phytochemical compounds, antibacterial test against S. aureus in vitro, toxicity test using Artemia salina, characterization of gel formulation, antibacterial test of gel formulation against S.aureus and antibacteria performance from formulated hand sanitizer. The phytochemical compounds detected in extract were from flavonoid and tannin groups with antibacterial activity observed at concentration of 15 and 20% with 8.0 and 9.6 mm diameter of inhibition zones respectively.The Lethal Concentration 50 (LC50) value was obtained at 162,18 ppm while administration of hand sanitizer reduced S.aureus up to 17.4 colonies in average.

Paper Citation

in Harvard Style

Asahan I., Silaban S., Harahap A. and Suryanto D. (2018). Antibacterial-based Hand Sanitizer of Biwa Leaves’ Extract (Eriobotrya japonica (Thunb) Lindl) from Tanah Karo.In Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR, ISBN 978-989-758-449-7, pages 1076-1081. DOI: 10.5220/0010102110761081

in Bibtex Style

@conference{icosteerr18,
author={Irfan Asahan and Slamet Silaban and Arif M. Harahap and Dwi Suryanto},
title={Antibacterial-based Hand Sanitizer of Biwa Leaves’ Extract (Eriobotrya japonica (Thunb) Lindl) from Tanah Karo},
booktitle={Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,},
year={2018},
pages={1076-1081},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0010102110761081},
isbn={978-989-758-449-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Conference of Science, Technology, Engineering, Environmental and Ramification Researches - Volume 1: ICOSTEERR,
TI - Antibacterial-based Hand Sanitizer of Biwa Leaves’ Extract (Eriobotrya japonica (Thunb) Lindl) from Tanah Karo
SN - 978-989-758-449-7
AU - Asahan I.
AU - Silaban S.
AU - Harahap A.
AU - Suryanto D.
PY - 2018
SP - 1076
EP - 1081
DO - 10.5220/0010102110761081