The Efficacy of Super-oxidised Hydrogel and Solution Compared to Potassium Permanganate Dressing for the Management of Cellulitis

Sabrina Ab Wahab, Tarita Taib, Rohna Ridzwan

2018

Abstract

Cellulitis causes local residual inflammation which delays clinical resolution. Studies have shown that super-oxidised hydrogel and solution improves skin and soft tissue infection. This is a multicentre, prospective, open-label, comparative clinical study involving adults ≥ 18 years old, efficacy comparison between two methods of dressing; super-oxidised hydrogel and solution dressing compared to potassium permanganate dressing, assessment of reduction of local inflammation; erythema, oedema and cellulitis severity score. Thirty patients with 2 different sites of cellulitis received the super-oxidised hydrogel and solution dressing (SO Group) and potassium permanganate (KMnO4 Group) wet wrap dressing at different sites of leg for 15 minutes, twice a day reviewed at end-of-treatment (day 3 and/or day 7). SO Group when compared to KMnO4 Group showed difference in percentage of erythema reduction at Day 3 (50.05% vs 30.98%; p=0.001) and at Day 7 (71.10% vs 59.05 %; p=0.045); with median reduction in limb circumference at Day 3 (1.90 cm vs 0.80 cm; p=0.001) and Day 7 (3.00 cm vs 1.80 cm; p=0.021). Both dressings showed reduction of cellulitis severity score (total score of 21); with median reduction of score at Day 3 (6.0 vs 5.5; p=0.123) and Day 7(12.0 vs 11.0; p=0.567), and significant difference only in erythema scores (p=0.029). Diabetes mellitus, bullous type, and disease recurrence were significant associated factors. In conclusion, super-oxidised hydrogel and solution is more effective in improving local erythema and oedema compared to potassium permanganate dressing, in patients with cellulitis albeit no difference in the reduction of total cellulitis severity score.

Paper Citation

in Harvard Style

Wahab S., Taib T. and Ridzwan R. (2018). The Efficacy of Super-oxidised Hydrogel and Solution Compared to Potassium Permanganate Dressing for the Management of Cellulitis.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 60-63. DOI: 10.5220/0008150800600063

in Bibtex Style

@conference{rcd18,
author={Sabrina Ab Wahab and Tarita Taib and Rohna Ridzwan},
title={The Efficacy of Super-oxidised Hydrogel and Solution Compared to Potassium Permanganate Dressing for the Management of Cellulitis},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={60-63},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008150800600063},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - The Efficacy of Super-oxidised Hydrogel and Solution Compared to Potassium Permanganate Dressing for the Management of Cellulitis
SN - 978-989-758-494-7
AU - Wahab S.
AU - Taib T.
AU - Ridzwan R.
PY - 2018
SP - 60
EP - 63
DO - 10.5220/0008150800600063