Effect of Sunflower Seed Oil Moisturizer Creams on Transepidermal Water Loss in Atopic Dermatitis Pediatric Patients

Inne Arline Diana, Reiva Farah Dwiyana, Srie Prihianti Gondokaryono, Ineke Winda, Ayu Nur Ain, Roni Aldiano, Imelda Pardede, Hendra Gunawan, Kristina Makarti

2018

Abstract

Atopic dermatitis (AD) is a chronic disease associated with disruption of skin barrier. There is an increase of transepidermal water loss (TEWL) in AD, therefore moisturizers application is essential. Sunflower seed oil (SSO) is one of natural moisturizer contain essential fatty acid that has emollient and occlusive effect. The aim of this study was to ascertain the effect of SSO on TEWL in AD pediatric patients. A hundred and twenty-four pediatric subjects with and without history of AD recruited into one cross-sectional study and three randomize-controlled studies, including the measurement of TEWL on six anatomical sites, the effect of 15% SSO moisturizer cream in healthy skin, comparison of 15% SSO moisturizer cream to controlled, and comparison of 20% SSO moisturizer to 5% urea moisturizer cream in AD patients, respectively. The moisturizer was applied twice daily on forearm or lower leg for two weeks. The TEWL values was measured by Tewameter® 300. The result showed that the highest TEWL values on the extensor part of lower leg (10.72 g/m2/h). The application of 15% SSO moisturizer showed a positive impact on skin barrier by reducing TEWL value in healthy skin (average decrease 9.34 g/m2/h, p< 0.01). TEWL decrement value between 15% SSO group compared to controlled group were not significant (p= 0.283). While, TEWL decrement value of 20% SSO group had similar results compared to 5% urea group (p= 0.309). We concluded that 20% SSO can be used as an alternative and can work as well as urea on AD pediatric patients.

Paper Citation

in Harvard Style

Diana I., Dwiyana R., Gondokaryono S., Winda I., Ain A., Aldiano R., Pardede I., Gunawan H. and Makarti K. (2018). Effect of Sunflower Seed Oil Moisturizer Creams on Transepidermal Water Loss in Atopic Dermatitis Pediatric Patients.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 108-112. DOI: 10.5220/0008151901080112

in Bibtex Style

@conference{rcd18,
author={Inne Arline Diana and Reiva Farah Dwiyana and Srie Prihianti Gondokaryono and Ineke Winda and Ayu Nur Ain and Roni Aldiano and Imelda Pardede and Hendra Gunawan and Kristina Makarti},
title={Effect of Sunflower Seed Oil Moisturizer Creams on Transepidermal Water Loss in Atopic Dermatitis Pediatric Patients},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={108-112},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008151901080112},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - Effect of Sunflower Seed Oil Moisturizer Creams on Transepidermal Water Loss in Atopic Dermatitis Pediatric Patients
SN - 978-989-758-494-7
AU - Diana I.
AU - Dwiyana R.
AU - Gondokaryono S.
AU - Winda I.
AU - Ain A.
AU - Aldiano R.
AU - Pardede I.
AU - Gunawan H.
AU - Makarti K.
PY - 2018
SP - 108
EP - 112
DO - 10.5220/0008151901080112