Correlation between Density of House Dust Mites and Relapse Rate of Atopic Dermatitis: A Cross Sectional Study

Gardenia Akhyar

2018

Abstract

Background: Inhaled allergens especially house dust mites (HDM) greatly contribute to the occurrence of atopic dermatitis (AD). It is supported by research conducted by Collof (1992) that measured the density of HDM on mattresses of AD and mattresses of non atopic healthy people and the result of HDM density on mattresses of patients with AD is higher than non atopic healthy controls. Teplitsky et al (Jerussalem, 2008) reported that patients with AD showed a higher prevalence of mites on their skin than did healthy individuals, which could be involved in allergic sensitization and disease exacerbation. The present study aims to investigate the correlation between density of HDM and relapse rate of AD, confirmed with skin prick test (SPT) of HDM. Methods: In present study 30 participants were included. Dust from each bedroom was collected. The density of HDM was calculated while the participants were checked their sensitivity of HDM by SPT. Establishing the diagnosis of AD based on Hanifin-Radjka criteria. Each participant was asked about recurrence of AD in the last three months. Results: Seven (23.3%) samples had moderate density of HDM while 23 (76.7%) had low density of HDM. From anamnesis, 10 (33.3%) participants were diagnosed with AD and SPT showed that 50% samples were sensitive against HDM. Out of 10 AD participants, 8 (80%) were positive with HDM allergens. All 10 participants with AD had relapse within three months. Conclusion: Out of 10 participants with atopic dermatitis, two (20%) had moderate density of HDM in bedroom (p>0.05). Also, from seven samples with moderate density of HDM, three (20%) were sensitive against HDM (p>0.05). About 80% of AD showed sensitivity against HDM while all 10 AD participants had relapse within last three months indicated that HDM allergen could induce exacerbation of disease in AD, but the correlation between HDM density and the relapse rate could not be proven yet. This present study suggests further investigation with larger samples size.

Paper Citation

in Harvard Style

Akhyar G. (2018). Correlation between Density of House Dust Mites and Relapse Rate of Atopic Dermatitis: A Cross Sectional Study.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 253-256. DOI: 10.5220/0008155102530256

in Bibtex Style

@conference{rcd18,
author={Gardenia Akhyar},
title={Correlation between Density of House Dust Mites and Relapse Rate of Atopic Dermatitis: A Cross Sectional Study},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={253-256},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008155102530256},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - Correlation between Density of House Dust Mites and Relapse Rate of Atopic Dermatitis: A Cross Sectional Study
SN - 978-989-758-494-7
AU - Akhyar G.
PY - 2018
SP - 253
EP - 256
DO - 10.5220/0008155102530256