The Combination Therapy of Microneedling and Subcision with Platelet Rich Plasma (PRP) versus Platelet Rich Fibrin Matrix (PRFM) on Rolling and Boxscar Type Acne Scar: Case Series

Ance Imelda Betaubun, Etty Farida, Anggana Rafika Paramitasari, Willa Damayanti, Susanti Rosmala Dewi, Moerbono Mochtar, Indah Julianto

2018

Abstract

Background: Scarring is an unfortunate and frequent complication of acne vulgaris, resulting in significant psychological distress for patients. They have been subclassified into ice pick, boxcar, and rolling scars. Subcision and microneedling are some of therapeutic modalities in the form of acne scar. Platelet-rich plasma (PRP) has been evaluated for its potential benefits in the treatment of acne scars. In addition to platelets and their products, the presence of a fibrin matrix (PRFM) can enhances the delivery of growth factors. Objectives: investigate the efficacy of combination therapy using subcision, microneedling with application of PRP and PRFM in rolling and box acne scars. Methods: To observed the case reports from patients admitted to the hospital until patient returns. Case: 2 male patients, 28 and 30 years old, having acne scars in their faces since 5 years ago. They had no previous treatment until they came to dr.Moewardi general hospital a few months ago. After physical examination, we diagnosed them with box and rolling scars. We applied PRFM in their scars, followed by microneedling and subcision. Then, we injected PRP in that region. Conclusions: Giving injury to the dermis by microneedling acts in synergy with act of PRP and PRFM, which will modify healing response by releasing cytokines and growth factors, thus will induce remodeling of acne scars.

Paper Citation

in Harvard Style

Betaubun A., Farida E., Paramitasari A., Damayanti W., Dewi S., Mochtar M. and Julianto I. (2018). The Combination Therapy of Microneedling and Subcision with Platelet Rich Plasma (PRP) versus Platelet Rich Fibrin Matrix (PRFM) on Rolling and Boxscar Type Acne Scar: Case Series.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 373-376. DOI: 10.5220/0008157703730376

in Bibtex Style

@conference{rcd18,
author={Ance Imelda Betaubun and Etty Farida and Anggana Rafika Paramitasari and Willa Damayanti and Susanti Rosmala Dewi and Moerbono Mochtar and Indah Julianto},
title={The Combination Therapy of Microneedling and Subcision with Platelet Rich Plasma (PRP) versus Platelet Rich Fibrin Matrix (PRFM) on Rolling and Boxscar Type Acne Scar: Case Series},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={373-376},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008157703730376},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - The Combination Therapy of Microneedling and Subcision with Platelet Rich Plasma (PRP) versus Platelet Rich Fibrin Matrix (PRFM) on Rolling and Boxscar Type Acne Scar: Case Series
SN - 978-989-758-494-7
AU - Betaubun A.
AU - Farida E.
AU - Paramitasari A.
AU - Damayanti W.
AU - Dewi S.
AU - Mochtar M.
AU - Julianto I.
PY - 2018
SP - 373
EP - 376
DO - 10.5220/0008157703730376