Fishtank Granuloma Treated with Combination of Minocycline and Rifampicine

Alfonsus Rendy Laksditalia Nugroho, Taufiq Hidayat, Lita Setyowatie, Krisna Ariaputra, Diah Prabawati Retnani

2018

Abstract

Fishtank granuloma is atypical mycobacterium infection with Mycobacterium marinum as causative agent, primary risk of this condition are exposure with aquatic environment. It has no standard therapy, meanwhile it is imperative to begin therapy as soon as possible before bad prognosis happen due to ascending infection from skin to tenosynovium. Men, 40 years old complains from painful bumps in the back of the hand, ulcerating and indurated. Patient had undergone several therapies, but there were no improvement. Patient got hobby of nurturing koi fishes, similar lesion found on patient’s fishes. General examination shows pain score was 6/10. Dermatological examination dorsal manus dextra, with localized distribution, shows erythematous nodules, well defined, quantity 6, size 0,5–2 cm, with ulcers, crusts and scales. Histopathological examination shows poorly formed granulation tissues. Epidermis shows acanthosis and some absent, while dermis shows connective tissue with many blood vessels and sparse inflammatory cells of neutrophil, lymphocyte and histiocyte. No visible datia cells and caseous necrosis. Blood count shows limphocytosis and slight increase of ESR. Patient being diagnosed as fishtank granuloma, got minocycline 2x100 mg, rifampicine 1x600 mg for three months. Lesion healed with scar, pain score reduced to zero were achieved in second month. Therapy continued one month after complete healing. Fishtank granuloma often misdiagnose and leads to late initial therapy, meanwhile this infection tend to be persistent and unable to heal spontaneously. Combination of minocycline and rifampicine can increase therapeutical efectivity and may support establishing diagnosis of fishtank granuloma.

Paper Citation

in Harvard Style

Nugroho A., Hidayat T., Setyowatie L., Ariaputra K. and Retnani D. (2018). Fishtank Granuloma Treated with Combination of Minocycline and Rifampicine.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 393-397. DOI: 10.5220/0008158203930397

in Bibtex Style

@conference{rcd18,
author={Alfonsus Rendy Laksditalia Nugroho and Taufiq Hidayat and Lita Setyowatie and Krisna Ariaputra and Diah Prabawati Retnani},
title={Fishtank Granuloma Treated with Combination of Minocycline and Rifampicine},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={393-397},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008158203930397},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - Fishtank Granuloma Treated with Combination of Minocycline and Rifampicine
SN - 978-989-758-494-7
AU - Nugroho A.
AU - Hidayat T.
AU - Setyowatie L.
AU - Ariaputra K.
AU - Retnani D.
PY - 2018
SP - 393
EP - 397
DO - 10.5220/0008158203930397