The Diagnostic Approach to Cutaneous Metastases of Adenocarcinoma of the Prostate: A Case Report

Peppy Fourina, Riesye Arisanty, Sri Adi Sularsito, Lili Legiawati, Rahadi Rihatmadja, Shannaz Nadia Yusharyahya

2018

Abstract

The incidence of prostate cancer has increased all over the world, likely due to better detection methods. It becomes one of the most common cancers among elderly men. Almost all cases of prostate cancer are adenocarcinoma. The most common sites for metastases are lymph nodes and bone. We present a case of a 67- year-old man with an ulcer on his lower back for the past 6 months. Three years ago, he was diagnosed with poorly differentiated adenocarcinoma of the prostate with bone metastases. On physical examination, there was a solitary, 2x2x1 cm ulcer with elevated border and yellowish slough. The ulcer was painful and surrounded by erythematous and indurated tissues. There is no inguinal lymphadenopathy. Despite antibiotics, conventional and modern wound dressing, no significant improvement was noted. Considering the history of malignancy, skin biopsy was performed. Histopathological examination revealed scattered atypical cells around the blood vessels that stained positively with prostate-spesific antigen (PSA) and alpha-methylacyl-CoA racemase (AMACR), confirming cutaneous metastases of AP. Metastasis of AP to the skin is rare, and indicates a poor prognosis. Early recognition of cutaneous spread manifesting as ulcer that does not respond to proper treatment in the background of malignancy is important.

Paper Citation

in Harvard Style

Fourina P., Arisanty R., Sularsito S., Legiawati L., Rihatmadja R. and Yusharyahya S. (2018). The Diagnostic Approach to Cutaneous Metastases of Adenocarcinoma of the Prostate: A Case Report.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 424-427. DOI: 10.5220/0008158904240427

in Bibtex Style

@conference{rcd18,
author={Peppy Fourina and Riesye Arisanty and Sri Adi Sularsito and Lili Legiawati and Rahadi Rihatmadja and Shannaz Nadia Yusharyahya},
title={The Diagnostic Approach to Cutaneous Metastases of Adenocarcinoma of the Prostate: A Case Report},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={424-427},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008158904240427},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - The Diagnostic Approach to Cutaneous Metastases of Adenocarcinoma of the Prostate: A Case Report
SN - 978-989-758-494-7
AU - Fourina P.
AU - Arisanty R.
AU - Sularsito S.
AU - Legiawati L.
AU - Rihatmadja R.
AU - Yusharyahya S.
PY - 2018
SP - 424
EP - 427
DO - 10.5220/0008158904240427