An Indistinguishable Case of Zinc Deficiency: Acquired Zinc Deficiency or Acrodermatitis Enteropathica?

Putri Reno Sori, Reiva Farah Dwiyana, Yuri Yogya, Inne Arline Diana, R. M. Rendy, Ariezal Effendi

2018

Abstract

Zinc (Zn) is an essential micronutrient in growth and development in children. In some condition, zinc deficiency occurred due to genetic or non-genetic caused. Skin disorders due to Zn deficiency are differentiated into acrodermatitis enteropathica (AE) and acquired zinc deficiency (AZD). These conditions are often indistinguished, since they have same skin disorders. However, AE is caused by genetic disorder that need long-life Zn supplementation, and the other hand, AZD occurred by imbalance intake of Zn, especially from breast milk. Therefore, further examination for baby and mother are required. Here, we describe a case report of a 3-month old boy with zinc deficiency. Skin disorders evolved since the patient was 2-month old as symmetrical dermatitis in perioral, acral, and skin folds area, accompanied with diarrhea. Patient was born prematurely at 34-week of gestation and was a breast-fed infant. The diagnosis of AZD was established based on typical skin lesion, diarrhea, and low serum Zn level. This decreased of serum Zn also found in his mother. Patient was treated with 10 mg Zn sulphate supplement once daily and clinical improvement was obtained after five days supplementation. Zinc level in patient remained high after one month discontinuation of Zn supplement. Clinically, AZD is difficult to distinguish with AE, thus zinc level examination in baby and mother are required, as well as observation during and after discontinued of zinc supplementation, to support the diagnosis, both for AE or AZD.

Paper Citation

in Harvard Style

Sori P., Dwiyana R., Yogya Y., Diana I., Rendy R. and Effendi A. (2018). An Indistinguishable Case of Zinc Deficiency: Acquired Zinc Deficiency or Acrodermatitis Enteropathica?.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 489-492. DOI: 10.5220/0008160404890492

in Bibtex Style

@conference{rcd18,
author={Putri Reno Sori and Reiva Farah Dwiyana and Yuri Yogya and Inne Arline Diana and R. M. Rendy and Ariezal Effendi},
title={An Indistinguishable Case of Zinc Deficiency: Acquired Zinc Deficiency or Acrodermatitis Enteropathica?},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={489-492},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008160404890492},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - An Indistinguishable Case of Zinc Deficiency: Acquired Zinc Deficiency or Acrodermatitis Enteropathica?
SN - 978-989-758-494-7
AU - Sori P.
AU - Dwiyana R.
AU - Yogya Y.
AU - Diana I.
AU - Rendy R.
AU - Effendi A.
PY - 2018
SP - 489
EP - 492
DO - 10.5220/0008160404890492