A Rare Case of Erythroderma in a Primary Cutaneous Anaplastic Large Cell Lymphoma: A Diagnostic Challenge

Agung Mohamad Rheza, Irene Dorthy Santoso, Ika Anggraini, Venessa Fikri, Riesye Arisanty, Selviyanti Padma, Sondang P. Sirait

2018

Abstract

Anaplastic large cell lymphoma (ALCL) is a rare form of non-Hodgkin's lymphoma. It usually originates in lymph nodes, although its origin in other tissues, including skin, has been reported. Identification of the lymphoid activation antigen (CD30) has now clearly established the lymphoid origin of ALCL. Recent reports suggest that in some cases cutaneous ALCL pre-existing skin disease may be a feature. This is usually mycosis fungoides (MF), although psoriasis has also been reported. A diagnosis of ALCL is usually made by a dermatologist following a series of diagnostic tests and procedures, including physical examination and history, blood tests, skin biopsy and/or lymph node biopsy
, immunophenotyping may also be done to identify specific types of lymphoma. In selected cases, molecular tests may be helpful in establishing the diagnosis. A fifty one years old man came with chief complaint of reddish, pruritic patch all over his body and nodules on his right axilla and buttock. Two skin biopsies were collected, resulted a spongiotic psoriasiform hyperplasia found in drug eruption and mixed cellularity Hodgkin lymphoma. Immunohistochemistry (IHC) shows positive CD30 and CD43, Ki-67 on 80% of the cells and negative CD3, CD20, ALK, CD1a, CD15, PAX-5, AE1/AE3 with conclusion of non-Hodgkin lymphoma - ALCL.

Paper Citation

in Harvard Style

Rheza A., Santoso I., Anggraini I., Fikri V., Arisanty R., Padma S. and Sirait S. (2018). A Rare Case of Erythroderma in a Primary Cutaneous Anaplastic Large Cell Lymphoma: A Diagnostic Challenge.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 500-504. DOI: 10.5220/0008160705000504

in Bibtex Style

@conference{rcd18,
author={Agung Mohamad Rheza and Irene Dorthy Santoso and Ika Anggraini and Venessa Fikri and Riesye Arisanty and Selviyanti Padma and Sondang P. Sirait},
title={A Rare Case of Erythroderma in a Primary Cutaneous Anaplastic Large Cell Lymphoma: A Diagnostic Challenge},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={500-504},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008160705000504},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - A Rare Case of Erythroderma in a Primary Cutaneous Anaplastic Large Cell Lymphoma: A Diagnostic Challenge
SN - 978-989-758-494-7
AU - Rheza A.
AU - Santoso I.
AU - Anggraini I.
AU - Fikri V.
AU - Arisanty R.
AU - Padma S.
AU - Sirait S.
PY - 2018
SP - 500
EP - 504
DO - 10.5220/0008160705000504