Best Effect of Progressive Muscle Relaxation (PMR) on Children:
A Systematic Review
Casman
1
and Nani Nurhaeni
2
1
Department of Pediatric Nursing, RS Husada’s School of Health Science, Jakarta, Indonesia
2
Department of Pediatric Nursing,Universitas Indonesia, Depok, Indonesia
Keywords: Progressive Muscle Relaxation, Children, Systematic Review.
Abstract: Objectives: Progressive Muscle Relaxation (PMR) showed good benefit in adult such as reduction stress,
this systematic review to synthesis evidence on progressive muscle relaxation effect in children and
investigates minimum ages to started the PMR. Methods: A literature search was conducted on ProQuest,
EBSCOhost, ScienceDirect, and SpringerLink. The systematic review consisted of retrieving articles
published between 2008 until 2018, using the keywords “progressive muscle relaxation” and child or
pediatric or adolescent. Results: Overall more than 500 potential articles were screened, of which 10 were
eligible. All of articles showed PMR is significant to reduce stress and anxiety of children, 50% articles
showed the participant’s is school age and adolescent with minimum age is 4 year or older. Conclusions:
progressive muscle relaxation is good technic to reduction stress in children, also increased good mood and
attention of children. In closing, further evidence is needed to delineate the obstacle of doing PMR in
children, by qualitative or quantitative research especially in Indonesia.
1 INTRODUCTION
Stress is a result of discrepancy between individual
reaction to difficulties or limitations and his
capability of managing and overcoming important
situations. Children’s strategies to adapt with stress
depend on their abilities as well as their
accomplishment to use the abilities. The stressor
causes emotion changes on that raise stress (Terzian,
Moore, & Nguyen, 2010). Stress becomes the main
cause of negative behaviour in childhood. The
negative behaviour includes anxiety, depression,
memory and language disorder, and reduction of
academic ability (Evans & Schamberg, 2009).
Children frequently encounter difficulty to adapt
stress., Furthermore, when they feel difficult to
express their stress, they will experience emotion
changes, behaviour, or physical disorder. other
physical disorders include increase of muscle
tension, headache, stomach illness, eating and
sleeping disruption, and lack of energy. The emotion
changes include nervousness, worry, unenthusiastic
feeling, anger, revenge to their peer, shyness or self-
isolated behaviour, powerlessness, and desperation.
The behaviour changes include bad habit of eating
and weight loss/gain in a short time (Terzian et al.,
2010).
Relaxation is one of effective non-
pharmacological techniques to decrease stress
because it influences mental and physical conditions,
depression, mood, anxiety, and self-blaming. Several
studies prove that well-ordered and consistent
relaxation can decrease stress. Therefore, nurses are
expected to be able to provide education of
relaxation benefits for patients because the education
is cheap and easy to practice (Gorji, Davanloo, &
Heidarigorji, 2014).
One of the relaxation techniques is Progressive
Muscle Relaxation (PMR). Jacobson (1976) explains
that relaxation to several muscles can be practiced
by making the muscles maximally strain, and then
loosening it until the muscle is relaxed. Jacobson
finds that systematic strains and slow extrication on
some muscles enable someone to feel different
sensation of muscle strain and relaxation. This
process makes someone experience deep relaxation.
Jacobson suggests that relaxation and contraction are
successively conducted in sixteen muscle groups.
However, generally PMR is practiced by adults.
12
Casman, . and Nurhaeni, N.
Best Effect of Progressive Muscle Relaxation (PMR) on Children: A Systematic Review.
DOI: 10.5220/0008199200120017
In Proceedings of the 1st International Conference of Indonesian National Nurses Association (ICINNA 2018), pages 12-17
ISBN: 978-989-758-406-0
Copyright
c
2020 by SCITEPRESS Science and Technology Publications, Lda. All rights reserved
1.1 Purpose
This systematic review proposes to analyze the
influence of PMR on children’s decrease of stress
and to investigate the right time to start PMR on
children.
2 METHODS
The systematic review will be reported in line with
the guidlines from the Cochrane Handbook of
Systematic Reviews of Interventions (versión 5.1.0)
(Higgins, J. P. T., Green, S., & Collaboration, 2011),
also used the recommendations of the PRISMA
statement (Urrútia, G., & Bonfill, 2010).
2.1 Criteria of Article Selection
The selected articles were articles employing true-
experimental method or quasi-experimental design
which analyzed the influence of PMR on the
decrease of stress, anxiety, or other positive aspects
such as increasing attention or interest. The selected
articles were articles written in English and
published in the last 10 years, and articles with
children as their population
2.2 Search Strategy
The complete search was conducted in four
databases: ProQuest, EBSCOhost, ScienceDirect,
and SpringerLink. The search was conducted from
October to November 2018, with the keywords
progressive muscle relaxation, child, paediatric, and
adolescent
2.3 Articles Selection
After searching articles in several databases, the first
step of selection was to read titles and abstracts of
the articles. Then, the chosen articles were verified
by two reviewers. The two reviewers discussed to
select the articles by considering inclusive and
exclusive criteria. The complete selection process is
presented in Fig.1.
3 RESULT
The result of the search reveals that 551 articles are
found, and only 23 complete articles are analyzed.
Finally, 10 appropriate articles for the inclusive and
exclusive criteria are selected.
3.1 Article Characteristic
The total respondents of the articles are 870
children. Six articles focus on the effect (time
duration and frequency) of decreasing the level of
stress and anxiety (Chan et al., 2015; Hashim &
Zainol, 2015; Manjushambika, Prasanna,
Vijayaraghavan, & Sushama, 2017; Mason,
Burkhart, & Lazebnik, 2018; Olmedilla-zafra,
Rubio, Ortega, & García-mas, 2017; Srilekha,
Soumendra, & Chattopadhyay, 2013), 3 articles
analyze the effect of PMR on increasing
attention/interest, the ability to answer the questions,
and language retardation (Chan, Sze, Siu, Lau, &
Cheung, 2013; McKenney, Broach, & Mullen, 2018;
Murray, Scott, Connolly, & Wells, 2018),
Meanwhile, 1 remaining article discusses the impact
of PMR on children’s headache (Jong et al., 2018).
Figure 1: Article Selection.
There are 5 articles employ true-experimental
design (Chan, Sze, Siu, Lau, & Cheung, 2013; Jong
et al., 2018; Manjushambika, Prasanna,
Vijayaraghavan, & Sushama, 2017; Murray, Scott,
Connolly, & Wells, 2018; Olmedilla-zafra, Rubio,
Ortega, & García-mas, 2017), 4 articles employs
Records identified through
database searching
(n=551)
Records after duplicate
removed
(
n=537
)
Records screened
(
n=537
)
Full-text articles assessed
for eligibility
(n=23)
Articles selected
ProQuest (n=3)
EBSCOhost (n=2)
ScienceDirect (n=4)
SpringerLink (n=1)
Records
excluded
(title and
abstract)
(n=514)
Full-text
articles
excluded
(with criteria
and bias)
(n=13)
Best Effect of Progressive Muscle Relaxation (PMR) on Children: A Systematic Review
13
quasi-experimental design (Chan et al., 2015;
Hashim & Zainol, 2015; McKenney, Broach, &
Mullen, 2018; Srilekha, Soumendra, &
Chattopadhyay, 2013), and 1 article employs cohort
method (Mason, Burkhart, & Lazebnik, 2018). The
explanation of selected articles is presented in Table
1.
The analysis of selected articles reveals that the
articles have discussed the procedures of PMR,
duration and sessions to practice PMR are different,
and PMR possibly influences the result. The
explanation of how the duration and frequency
session to practice PMR can influence stress,
anxiety, emotion control, and headech of children,
and in what age that children can practice PMR is
presented as follows:
3.2 Duration and Session of PMR
Children who are intervened PMR for 15-20 minutes
a day show the decrease of stress score from 133 to
116 in the first month, and the result becomes 117
after 3 months, p<0.05
(Manjushambika, Prasanna,
Vijayaraghavan, & Sushama, 2017). PMR of which
the duration is 25 minutes and which is practiced 6
to 12 sessions will effectively decrease anxiety,
depression, and stress. In addition, it increases
attention and interest (Hashim & Zainol, 2015).
PMR exercises (15 minutes a day or 3 days in a
week, conducted for 9 successive weeks) show
meaningful changes in all of the measurements of
research variables: p<0.001 for anxiety and p<0.005
for attention focus (Srilekha, Soumendra, &
Chattopadhyay, 2013). PMR with 30-minute
duration is effectively applied as a stress
management (Mason, Burkhart, & Lazebnik, 2018).
Practicing PMR once in a week for an hour within 3
months will meaningfully overcome stress
(Olmedilla-zafra, Rubio, Ortega, & García-mas,
2017). Group of PMR experiences stress level
decrease (Z=-2.14, p =0.032) in which PMR is
conducted once in a day for 30 minutes within 5
days (Chan et al., 2015).
The effect of PMR is good not only for anxiety
and stress, but also for other functions in children.
Children who get 12 session of PMR will be able to
increase their short memories (Hashim & Zainol,
2015). Exercises conducted once a week for 1 hour
in each session will effectively decrease children’s
illness with value p < 0.001, r
2
=0.309 (Olmedilla-
zafra, Rubio, Ortega, & García-mas, 2017). PMR
with 20–minute duration will make autism children
experience increase of emotion control (Chan, Sze,
Siu, Lau, & Cheung, 2013). Practicing PMR once in
a day within 3 months will effectively decrease
duration, frequency, and degree of headeach(Jong et
al., 2018). PMR with 20–minute duration in 3
sessions of each week can increase time to answer
questions or assist mentally disabled children to
become more perceptive. The PMR intervention
group requires 58 seconds while the control group
requires 70 seconds to answer a question (Chan, Sze,
Siu, Lau, & Cheung, 2013). However, PMR with 11-
minute duration does not meaningfully increase
children’s ability from language retardation
(Murray,
Scott, Connolly, & Wells, 2018).
3.3 Children’s Age
The 11 articles indicate that the children are 4-20
years old, in which the youngest is 4 years old(Chan
et al., 2015), and the oldest is 20 years old(Mason,
Burkhart, & Lazebnik, 2018).
4 DISCUSSION
The systematic review shows that there is positive
effects of PMR on children. There are several
variations of duration which has positive meaning to
the PMR training, they are 15 minute-duration of
PMR shows significance for children
(Manjushambika, Prasanna, Vijayaraghavan, &
Sushama, 2017; Srilekha, Soumendra, &
Chattopadhyay, 2013), 20 minutes (Chan, Sze, Siu,
Lau, & Cheung, 2013), 25 minutes (Hashim &
Zainol, 2015), 30 minutes (Chan et al., 2015; Mason,
Burkhart, & Lazebnik, 2018), and 60 minutes
(Olmedilla-zafra, Rubio, Ortega, & García-mas,
2017), but 11 minute-duration does not show
significance for children (Murray, Scott, Connolly,
& Wells, 2018). Longer duration of PMR in one
session will give more positive impacts to children.
Musthaq & Khan (2018) makes guidance of
PMR exercise, that is following the step bellow in
times 20 minutes.
a. To sit on a chair as comfortably as possible.
Keep your body loose, continues to light and
free.
b. Be calm and comfortable.
c. Keep your eye closed.
d. Avoid stray thoughts.
e. Avoid extra movements of the body.
f. During the part of the exercise cycle tense the
muscle tightly and hold for slow count of 5
seconds. (Repeat silently 1001, 1002, 1003,…)
ICINNA 2018 - The 1st International Conference of Indonesian National Nurses Association
14
g. During the relation part of exercise cycle relaxes
the muscle quickly and completely .let your mind
relax and appreciate how relaxed the muscle is
feeling for 10 seconds.
h. Try to keep all other muscles relaxed as you
exercise specific muscle group.
i. As you exercise from head to toe. Observe
changes like tightness and the development of
light and soothing sensations.
Table 1: Description of The Selected Studies.
(Authors, Year) &
Country
Result
(Jong et al., 2018)
Netherlands
Methode: RCT. Intervention group used mind-body techniques (transcendental meditation or hypnotherapy vs
Control group used progressive muscle relaxation, instrument used RCADS, CSI and PCQ.
Age of Sample: 131 children with 9 -18 years old.
Main Result: Headache frequency, the primary outcome, was significantly reduced in all groups (from 18.9
days to 12.5 and 10.5 at respectively 3 and 9 months; p <0.001), pain medication was significantly reduced in
all children at 3 months (p = 0.003) and 9 months (p = 0.032), but no significant differences were observed
between the three groups.
Author Conclusion: non-pharmacological techniques effectively reduce the number of primary headache in
children
(Mason, Burkhart, &
Lazebnik, 2018)
USA
Methode: Cohort. Intervention group participants received training in diaphragmatic breathing, progressive
muscle relaxation (30 minutes), and use of no-cost/low-cost exercise options.
Age of Sample: 86 adolescents with 11-20 years old.
Main Result: There was not a significant difference between the intervention group and the control group on
key study variables (generalized anxiety, depression, perceived stress, pre-inter- vention subjective units of
distress score, and pre-intervention coherence rates), SUDS scores was a significant ( p < 0.001), and HRV was
a significant (p = 0.003).
Author Conclusion: Integrated care model in a primary care setting is feasible and effective at improving
stress management.
(Chan et al., 2015)
Hong Kong
Methode: Exploratory trial using a pre-teste post-test control group design. PMR given to intervention group
for 30 minutes.
Age of Sample: 65 patients who diagnosis of cancer and still chemotherapy, aged 4-11 years. Main Result:
Group PMR had significantly lower levels of child anxiety (Z=-2.14, p =0.032) than education group, No
statistical differences in body weight, the occurrence of nausea and vomiting, the intake of antiemetics, and
anxiety level (p > 0.05) between the two intervention groups.
Author Conclusion: The intervention process and higher levels of perceived usefulness of intervention were
given by patients in the relaxation group compared to those in the education group.
(Manjushambika,
Prasanna,
Vijayaraghavan, &
Sushama, 2017)
India
Methode: RCT. Jacobson’s Progressive Muscle relaxation (JPMR) took about 15-20 minutes daily.
Age of Sample: 145 students, range of ages 11-17 year.
Main Result: JPMR was statistically significant (Mc Nemer Chi-square =16.06; p<0.001).We conclude that
JPMR was effective in reducing the stress significantly.
Author Conclusion: JPMR is effective in reducing educational stress among adolescents.
(Hashim & Zainol,
2015)
Malaysia
Methode: Quasi experiment used 25 min pre-recorded PMR compact disc (CD), DST for measured short-term
memory, DVT for measured attention, and DASS21 to measure depression, anxiety, and stress levels.
Age of Sample: 132 primary school students, 24% 10 years old, and 76% 11 years old.
Main Result: A significant difference among the groups in mean changes in short-term memory (F = 3.89, df =
2, and p < 0.05), 12 session PMR>6 session PMR or no Intervention group, and no significant differences were
observed among the groups in anxiety (p > 0.05), depression (p > 0.05), stress (p > 0.05), or sustained attention
(p > 0.05)
Author Conclusion: This particular finding may provide general support for the use of at least 12 sessions of
PMR training, to reduce stress level, increase attention and strength short-term memory.
(Chan, Sze, Siu,
Lau, & Cheung,
2013)
Hong Kong
Methode: RCT. Intervention group used Chinese mind-body intervention (Nei Yang Gong)
Control group used PMR (20 minutes)
Age of Sample: 48 students (autism child), range of ages 6-17 year.
Main Result: The results showed that there were significant and marginally significant Time (Pre vs Post) by
Group (Control vs Experimental) interaction effects on the two indices of the TOLDX, i.e., the frequency of
rule violation, F(1,34)=6.02, p=0.02, and the initial time, F(1,34)=3.25, p=0.08.
Author Conclusion: Nei Yang Gong and PMR had a positive effect in enhancing the self-control of children
with autism spectrum disorders, but elevated brain activity was not observed in the children practicing PMR.
Best Effect of Progressive Muscle Relaxation (PMR) on Children: A Systematic Review
15
Table 1: Description of The Selected Studies (cont.).
(Authors, Year) &
Country
Result
(Olmedilla-zafra,
Rubio, Ortega, &
García-mas, 2017)
Spain
Methode: RCT. Included the following modules:
1. Linking thoughts and emotions;
2. PMR breathing, imagery, passive and differential muscle relaxation;
3. Self- instructional and attention-focus training; and
4. Stress inoculation training.
Age of Sample: 74 male soccer players from, range of ages 17-19 year.
Main Result: There were no significant differences between the two groups regarding the average number of
injuries before the treatment, t(61)=-0.460, p =0.647. The differences between the groupswere significant in the
post-treatment phase (p=0.005, r
2
=0.077), showing that the average number of injurieswas larger in the non-
treatment group.
Author Conclusion: A program aimed at controlling the stress response can reduce the incidence of sports
injuries in young athletes.
(Murray, Scott,
Connolly, & Wells,
2018) England
Methode: RCT. Intervention used Attention Training Technique (ATT) and PMR (min. 11 minutes).
Age of Sample: 101 children (learning or behavioural difficulty) with 5.55 -6.82 years old.
Main Result: (Time: Pre vs Post) x 3 (Condition: ATT vs PMR vs no-intervention) revealed a significant
effect of time, F(1, 98)=32.79, p < .0005and no significant effect of condition, F(2, 98)=1.23, p=0.30.
Author Conclusion: ATT showed an improvement in delay of gratification that was significantly greater than
shown in the PMR or no-intervention group.
(Srilekha,
Soumendra, &
Chattopadhyay,
2013)
India & Bangladesh
Methode: Quasy experiment with pre post test. PMR given to intervention group for 15 minutes per day, 3
days per week for 9 consecutive weeks.
Age of Sample: 80 boys, age range of 9-12 year.
Main Result: PMR training showed significant changes on all of the variables measures in the desired
direction (p<0.001) for anxiety and (p<0.005) for attention.
Author Conclusion: Abbreviated version of PMR exercise training could be effective enough in modulating
heightened emotionality, reduction of dispositional anxiety and improvement in attentive performances.
(McKenney, Broach
& Mullen, 2018)
USA
Methode: Quasy experiment. Intervention used Multisensory training (MST) vs PMR 20 minutes.
Age of Sample: 8 students (behavior disorder), range of ages 7-14 year.
Main Result: Overall mean time on task score for all participants aſter MST was 72 seconds, compared to 58
seconds aſter the PRT sessions, and 70 seconds aſter the control sessions.
Author Conclusion: The mean time on task score for MST was slightly higher when compared to scores
obtained from the PRT and control sessions.
j. Relax by taking three deep breaths inhaling
through nose and exhaling through mouth after
each step.
k. Now make your body completely loose,
continuous feeling light and free
Children at least 4 years old possibly practice PMR.
The category of childhood is under 19 years old or
younger. This statement is in line with national law
in each country. In the age of 10-19 years old,
people will be categorized as adolescent(WHO,
2013). Four-year-old children eagerly have their first
valley of development process, because they can see
the world in a bigger perspective. Children start to
ask about the world and are interested in many
things, and thus, they feel anxious and even stressed
for facing unfamiliar world(Department of Health
Western Australia, 2018). It can be a stressor for
children because of unsupportive environment.
5 CONCLUSIONS
The systematic review reveals that PMR possibly
assists children to maximize positive influence of
relaxation to control stress and anxiety. PMR is
considered meaningful if it is practiced in at least
once a day for 15 minutes in each session of
training. Based on the result of analysis, PMR can
be practiced since the children are 4 years old.
Recommendation for researcher, effect PMR in
Children should be developed by researcher in
Indonesia.
ACKNOWLEDGEMENTS
The authors would like to thank Universitas
Indonesia and Perpusatakaan Nasional Indonesia for
facilitating the database search for conducting this
review. Our special thanks also to Dessie Wanda,
ICINNA 2018 - The 1st International Conference of Indonesian National Nurses Association
16
Ph.D and yeni Rustina, Ph. D., Universitas
Indonesia, for improving the writing style of this
manuscript in the EBP class.
REFERENCES
Chan, A. S., Sze, S. L., Siu, N. Y., Lau, E. M., & Cheung,
M. (2013). A Chinese Mind-Body Exercise Improves
Self-Control of Children with Autism: A Randomized
Controlled Trial. Plos One, 8(7), 1-12.
https://doi.org/10.1371/journal.pone.0068184
Chan, C. W. H., Wah, L., Kong, C., Cheung, J. S. S.,
Cheng, K. K. F., Wai, K., Tang, W. P. Y. (2015).
Feasibility of psychoeducational interventions in
managing chemotherapy-associated nausea and
vomiting ( CANV ) in pediatric oncology patients.
European Journal of Oncology Nursing, 19(2), 182–
190. https://doi.org/10.1016/j.ejon.2014.09.002
Department of Health Western Australia. (2018). Child
Develompment 4-5 year. Retrieved from
https://healthywa.wa.gov.au/Articles/A_E/Child-
development-4-5-years
Evans, G. W., & Schamberg, M. A. (2009). Childhood
poverty , chronic stress , and adult working memory.
PNAS, 106 (16) 6545–6549.
www.pnas.org/cgi/doi/10.1073/pnas.0811910106.
Gorji, M. A. H., Davanloo, A. A., & Heidarigorji, A. M.
(2014). The efficacy of relaxation training on stress ,
anxiety , and pain perception in hemodialysis patients.
Indian Journal of Nephrology, 24(6), 356-361.
https://doi.org/10.4103/0971-4065.132998
Hashim, H. A., & Zainol, N. A. (2015). Changes in
emotional distress , short term memory , and sustained
attention following 6 and 12 sessions of progressive
muscle relaxation training in 10 – 11 years old primary
school children. Psychology, Health & Medicine,
21(04),37–41, 37–41.
https://doi.org/10.1080/13548506.2014.1002851
Higgins, J. P. T., Green, S., & Collaboration, T. C. (2011).
Cochrane handbook for systematic reviews of
interventions version 5.1.0. Retrieved from
https://handbook-5-1.cochrane.org/
Jacobson. (1976). You must relax. London: Unwin
Paperbacks.
Jong, M. C., Boers, I., Wietmarschen, H. A. Van, Tromp,
E., Busari, J. O., Wennekes, R., Bekhof, J. (2018).
Hypnotherapy or transcendental meditation versus
progressive muscle relaxation exercises in the
treatment of children with primary headaches: a
multi-centre , pragmatic , randomised clinical study
European Journal of Pediatrics, 11(09): 1-7.
https://doi.org/10.1007/s00431-018-3270-3.
Manjushambika, R., Prasanna, B., Vijayaraghavan, R., &
Sushama, B. (2017). Effectiveness of Jacobson ’ s
Progressive Muscle Relaxation ( Jpmr ) on
Educational Stress among School Going Adolescents.
International Journal of Nursing Education, 9(4):
110-115. https://doi.org/10.5958/0974-
9357.2017.00106.4.
Mason, E. B., Burkhart, K. & Lazebnik, R. (2018).
Adolescent Stress Management in a Primary Care
Clinic. Journal of Pediatric Health Care, x(x), 1–8.
https://doi.org/10.1016/j.pedhc.2018.08.001
McKenney, A., Broach, M. E. & Mullen, L. V. (2018). A
Comparison of the Effects of Multisensory Therapy
and Progressive Relaxation Training on Time on Task
of Participants with Behavior Disorders. Therapeutic
Recreation Journal, LII(4), 329–349.
https://doi.org/10.18666/TRJ-2018-V52-I4-9032.
Murray, J., Scott, H., Connolly, C., & Wells, A. (2018).
Behaviour Research and Therapy The Attention
Training Technique improves Children â€
TM
s ability
to delay grati fi cation: A controlled comparison with
progressive relaxation. Behaviour Research and
Therapy, 104(2), 1–6.
https://doi.org/10.1016/j.brat.2018.02.003 Mushtaq,
B., & Khan, A. A. (2018). Jacobson Muscle
Relaxatation Technique. JOJ Nursing & Health Care,
8(1), 8–10.
https://doi.org/10.19080/JOJNHC.2018.08.555726
Olmedilla-zafra, A., Rubio, V. J., Ortega, E., & García-
mas, A. (2017). Physical Therapy in Sport
Effectiveness of a stress management pilot program
aimed at reducing the incidence of sports injuries in
young football ( soccer ) players. Physical Therapy in
Sport, 24, 53–59.
https://doi.org/10.1016/j.ptsp.2016.09.003
Srilekha, S., Soumendra S., & Chattopadhyay P . K.
(2013). Effect of o Muscle e Relaxati ion Train ning as
a Function of Im mprovem ment in Att tentivene ess in
Chil ldren. Procedia - Social and Behavioral Sciences,
91, 606–613.
https://doi.org/10.1016/j.sbspro.2013.08.460
Terzian, M., Moore, K. A., & Nguyen, H. N. (2010,
October 01). Assessing stress in children and youth: a
guide for out- of-school time program practitioners.
Retrieved from
https://www.childtrends.org/publications/assessing-
stress-in-children-and-youth-a-guide-for-out-of-
school-time-program-practitioners
Urrútia, G., & Bonfill, X. (2010). Declaración PRISMA:
una propuesta para mejorar la publicación de
revisiones sistemáticas y metaanálisis. Medicina
Clínica, 11(135), 507–511.
https://doi.org/https://doi.org/10.1016/j.medcli.2010.0
1.015
World Health Organization. (2013). HIV/AIDS. Retrieved
from
https://www.who.int/hiv/pub/guidelines/arv2013/intro/
keyterms/en/
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