Empirical Antibiotics Study on Pneumonia in Intensive Care Unit

Yeni Farida, Katarina Puspita, Zahra Yusvida

2018

Abstract

Microorganisms and inflammatory cells are present in the air sacs of the lungs in most pneumonia patients, preventing their lungs from functioning normally. The main treatment for pneumonia is antibiotics supported by physiotherapy. This study aimed to determine the pattern of empirical antibiotic use and bacterial etiology (sputum culture test) of ICU patients at a government hospital in Madiun, West Java. This descriptive research used retrospective data collected from January to December 2016. The samples were purposively selected based on specific inclusion criteria (i.e., patients diagnosed with pneumonia who received antibiotic therapy and had information on their bacterial culture data). The study examined the medical records of 77 subjects who were mostly aged 0-5 years old (67.5%). Acinetobacter baumannii was the most commonly isolated organism (42.1%), followed by Klebsiella pneumonia and Pseudomonas aeruginosa (15.79%). Meropenem was mostly used as a single antibiotic in pediatrics (24%), while ceftriaxone was most common in adult (16.22%). The most widely used combinations of antibiotics were ampicillin and gentamycin for pediatrics ICU patient (20%) and meropenem and metronidazole for adult patients (13.51%). Acinetobacter baumannii was completely resistant to Ampicillin-sulbactam and partially resistant to other beta-lactam antibiotics. Both Pseudomonas aeruginosa and Klebsiella pneumonia were completely resistant to Ampicillin and Ampicillinsulbactam.

Paper Citation

in Harvard Style

Farida Y., Puspita K. and Yusvida Z. (2018). Empirical Antibiotics Study on Pneumonia in Intensive Care Unit.In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD, ISBN 978-989-758-349-0, pages 48-53. DOI: 10.5220/0008239200480053

in Harvard Style

Farida Y., Puspita K. and Yusvida Z. (2018). Empirical Antibiotics Study on Pneumonia in Intensive Care Unit.In Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD, ISBN 978-989-758-349-0, pages 48-53. DOI: 10.5220/0008239200480053

in Bibtex Style

@conference{mich-phd18,
author={Yeni Farida and Katarina Puspita and Zahra Yusvida},
title={Empirical Antibiotics Study on Pneumonia in Intensive Care Unit},
booktitle={Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,},
year={2018},
pages={48-53},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008239200480053},
isbn={978-989-758-349-0},
}

in Bibtex Style

@conference{mich-phd18,
author={Yeni Farida and Katarina Puspita and Zahra Yusvida},
title={Empirical Antibiotics Study on Pneumonia in Intensive Care Unit},
booktitle={Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,},
year={2018},
pages={48-53},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008239200480053},
isbn={978-989-758-349-0},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,
TI - Empirical Antibiotics Study on Pneumonia in Intensive Care Unit
SN - 978-989-758-349-0
AU - Farida Y.
AU - Puspita K.
AU - Yusvida Z.
PY - 2018
SP - 48
EP - 53
DO - 10.5220/0008239200480053

in EndNote Style

TY - CONF

JO - Proceedings of the 1st Muhammadiyah International Conference on Health and Pharmaceutical Development - Volume 1: MICH-PhD,
TI - Empirical Antibiotics Study on Pneumonia in Intensive Care Unit
SN - 978-989-758-349-0
AU - Farida Y.
AU - Puspita K.
AU - Yusvida Z.
PY - 2018
SP - 48
EP - 53
DO - 10.5220/0008239200480053