Peripheral Blood Profiles of CCl4-Induced Wistar Rats after Date Seed Steeping Treatment

Saryono, Atikah Proverawati, Hernayanti Hernayanti, Ferry Effendi

2018

Abstract

A various household appliances that containing CCl4 can cause an inflammation. Utilization of date seed as an anti-inflammatory agent has never been done. The aim of the study was to explore the peripheral blood profiles of CCl4-induced wistar rat after steeped date seed treatment. An experimental study, post-test only with control group design was used. Rats were assigned into 6 groups. There are negative control, positive control, healthy control and treatment groups (dose 1; 3; 5 g/kg). Data collected were neutrophils, lymphocytes and monocytes. The data was compared between the groups with the ANOVA test and was followed by post hoc test. Induction of CCl4 causes an increase of monocytes, neutrophils and decreased lymphocytes number. Giving of dates seeds can reduce the number of monocytes and neutrophils but increase of lymphocytes number. A dose of 3 g/kg of dates seed has the same effect with a control group that given dexamethasone. The study showed for the first time anti-inflammatory of activity of steeped date seed can change the peripheral blood profile. Steeping of date seeds can repair tissue damage due to CCl4 exposure to be marked by accelerating the inflammatory process.

Paper Citation

in Harvard Style

Saryono., Proverawati A., Hernayanti H. and Effendi F. (2018). Peripheral Blood Profiles of CCl4-Induced Wistar Rats after Date Seed Steeping Treatment.In Proceedings of the 9th International Nursing Conference - INC, ISBN 978-989-758-336-0, pages 38-43. DOI: 10.5220/0008320100380043

in Bibtex Style

@conference{inc18,
author={Saryono and Atikah Proverawati and Hernayanti Hernayanti and Ferry Effendi},
title={Peripheral Blood Profiles of CCl4-Induced Wistar Rats after Date Seed Steeping Treatment},
booktitle={Proceedings of the 9th International Nursing Conference - INC,},
year={2018},
pages={38-43},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008320100380043},
isbn={978-989-758-336-0},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 9th International Nursing Conference - INC,
TI - Peripheral Blood Profiles of CCl4-Induced Wistar Rats after Date Seed Steeping Treatment
SN - 978-989-758-336-0
AU - Saryono.
AU - Proverawati A.
AU - Hernayanti H.
AU - Effendi F.
PY - 2018
SP - 38
EP - 43
DO - 10.5220/0008320100380043