The Modified Oral Minimal Model to Know Incretin Hormone Effect in Type 2 Diabetes Mellitus

Agus Kartono, Rojali Fadila, Heryanto Syafutra, Setyanto Tri Wahyudi, Tony Sumaryada

2018

Abstract

Simulation of glucose, insulin and incretin hormones concentrations in the blood is described using the modified oral minimal model that can be learned easily. In this study, the modified oral minimal model can also describe the kinetics of incretin hormone concentration to determine the level of insulin secretion in the body. Incretin hormone has been recognized as a major stimulus for insulin secretion after an oral glucose load. Based on the results of this study, subjects with type 2 diabetes have the smallest of incretin hormone concentration (115 ng/dL). The normal subjects have the highest of incretin hormone concentration (300 ng/dL). The simulations which have been done show that the deterministic coefficient (R2) value of each simulation has reached above 90%, meaning that all the simulations results are good.

Paper Citation

in Harvard Style

Kartono A., Fadila R., Syafutra H., Wahyudi S. and Sumaryada T. (2018). The Modified Oral Minimal Model to Know Incretin Hormone Effect in Type 2 Diabetes Mellitus.In Proceedings of the 7th Engineering International Conference on Education, Concept and Application on Green Technology - Volume 1: EIC, ISBN 978-989-758-411-4, pages 286-292. DOI: 10.5220/0009009802860292

in Bibtex Style

@conference{eic18,
author={Agus Kartono and Rojali Fadila and Heryanto Syafutra and Setyanto Tri Wahyudi and Tony Sumaryada},
title={The Modified Oral Minimal Model to Know Incretin Hormone Effect in Type 2 Diabetes Mellitus},
booktitle={Proceedings of the 7th Engineering International Conference on Education, Concept and Application on Green Technology - Volume 1: EIC,},
year={2018},
pages={286-292},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009009802860292},
isbn={978-989-758-411-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 7th Engineering International Conference on Education, Concept and Application on Green Technology - Volume 1: EIC,
TI - The Modified Oral Minimal Model to Know Incretin Hormone Effect in Type 2 Diabetes Mellitus
SN - 978-989-758-411-4
AU - Kartono A.
AU - Fadila R.
AU - Syafutra H.
AU - Wahyudi S.
AU - Sumaryada T.
PY - 2018
SP - 286
EP - 292
DO - 10.5220/0009009802860292