Variation in the Uncoupling Proteins Genes in Different Sports

Elvira Bondareva, Olga Parfenteva, Valentine Son’kin

2019

Abstract

Uncoupling protein (UCP) genes appear to be promising candidates for studying the effect of 'thrifty' genotypes on various aspects of modern human life, starting from susceptibility to obesity and cardiometabolic diseases and ending with sports talent. The study aims at studying directions of selection for polymorphic systems of the genes UCP1, UCP2 and UCP3 among athletes engaged in various sports. The study involved 268 people: 197 athletes (males: n=140; females: n=57) and 71 non-athletes as a control group (males: n=38; females: n=33). Buccal epithelium was used as a sample of biological material. Genomic DNA isolation and genotyping of samples for polymorphisms of UCP1 (rs1800592), UCP2 (rs660339), UCP3 (rs1800849) were performed at the premises of Lytech (Moscow). Differences in the distribution of genotype frequencies of the UCP1 and UCP2 genes between the subgroups within the sample of athletes are statistically significant (χ2 = 21.2 p = 0.006 and χ2 = 24.06 p = 0.002, respectively). Among the athletes representing various kinds of sports, the subgroups of aerobic, mixed cyclic and team sports demonstrate the directional selection of carriers of 'thrifty' genotypes of the studied genes. The subgroup of martial arts is characterized by the opposite direction in selection.

Paper Citation

in Harvard Style

Bondareva E., Parfenteva O. and Son’kin V. (2019). Variation in the Uncoupling Proteins Genes in Different Sports.In Proceedings of the 7th International Conference on Sport Sciences Research and Technology Support - Volume 1: icSPORTS, ISBN 978-989-758-383-4, pages 38-46. DOI: 10.5220/0008066800380046

in Bibtex Style

@conference{icsports19,
author={Elvira Bondareva and Olga Parfenteva and Valentine Son’kin},
title={Variation in the Uncoupling Proteins Genes in Different Sports},
booktitle={Proceedings of the 7th International Conference on Sport Sciences Research and Technology Support - Volume 1: icSPORTS,},
year={2019},
pages={38-46},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008066800380046},
isbn={978-989-758-383-4},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 7th International Conference on Sport Sciences Research and Technology Support - Volume 1: icSPORTS,
TI - Variation in the Uncoupling Proteins Genes in Different Sports
SN - 978-989-758-383-4
AU - Bondareva E.
AU - Parfenteva O.
AU - Son’kin V.
PY - 2019
SP - 38
EP - 46
DO - 10.5220/0008066800380046